SwePub
Sök i LIBRIS databas

  Extended search

onr:"swepub:oai:prod.swepub.kib.ki.se:227831918"
 

Search: onr:"swepub:oai:prod.swepub.kib.ki.se:227831918" > 17β-Estradiol suppr...

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist
  • Al-Qahtani, SMKarolinska Institutet (author)

17β-Estradiol suppresses visceral adipogenesis and activates brown adipose tissue-specific gene expression

  • Article/chapterEnglish2017

Publisher, publication year, extent ...

  • Walter de Gruyter GmbH,2017

Numbers

  • LIBRIS-ID:oai:prod.swepub.kib.ki.se:227831918
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:227831918URI
  • https://doi.org/10.1515/hmbci-2016-0031DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Both functional ovaries and estrogen replacement therapy (ERT) reduce the risk of type 2 diabetes (T2D). Understanding the mechanisms underlying the antidiabetic effects of 17β-estradiol (E2) may permit the development of a molecular targeting strategy for the treatment of metabolic disease. This study examines how the promotion of insulin sensitivity and weight loss by E2 treatment in high-fat-diet (HFD)-fed mice involve several anti-adipogenic processes in the visceral adipose tissue. Magnetic resonance imaging (MRI) revealed specific reductions in visceral adipose tissue volume in HFD+E2 mice, compared with HFD mice. This loss of adiposity was associated with diminished visceral adipocyte size and reductions in expression of lipogenic genes, adipokines and of the nuclear receptor

Added entries (persons, corporate bodies, meetings, titles ...)

  • Bryzgalova, GKarolinska Institutet (author)
  • Valladolid-Acebes, IKarolinska Institutet (author)
  • Korach-André, MKarolinska Institutet (author)
  • Dahlman-Wright, K (author)
  • Efendić, S (author)
  • Berggren, PO (author)
  • Portwood, N (author)
  • Karolinska Institutet (creator_code:org_t)

Related titles

  • In:Hormone molecular biology and clinical investigation: Walter de Gruyter GmbH29:1, s. 13-261868-18911868-1883

Internet link

Find in a library

To the university's database

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view