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  • Mashadi Fathali, Hoda,1983Chalmers tekniska högskola,Chalmers University of Technology (author)

Amperometry methods for monitoring vesicular quantal size and regulation of exocytosis release

  • Article/chapterEnglish2018

Publisher, publication year, extent ...

  • 2017-09-27
  • Springer Science and Business Media LLC,2018
  • electronicrdacarrier

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  • LIBRIS-ID:oai:research.chalmers.se:00a73124-8eeb-47cc-9bd2-9a988c6ed546
  • https://research.chalmers.se/publication/503744URI
  • https://doi.org/10.1007/s00424-017-2069-9DOI

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  • Language:English
  • Summary in:English

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  • Chemical signaling strength during intercellular communication can be regulated by secretory cells through controlling the amount of signaling molecules that are released from a secretory vesicle during the exocytosis process. In addition, the chemical signal can also be influenced by the amount of neurotransmitters that is accumulated and stored inside the secretory vesicle compartment. Here, we present the development of analytical methodologies and cell model systems that have been applied in neuroscience research for gaining better insights into the biophysics and the molecular mechanisms, which are involved in the regulatory aspects of the exocytosis machinery affecting the output signal of chemical transmission at neuronal and neuroendocrine cells.

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  • Cans, Ann-Sofie,1971Chalmers tekniska högskola,Chalmers University of Technology(Swepub:cth)cans (author)
  • Chalmers tekniska högskola (creator_code:org_t)

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  • In:Pflugers Archiv European Journal of Physiology: Springer Science and Business Media LLC470:1, s. 125-1340031-67681432-2013

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