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A low-gluten diet i...
A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults
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- Hansen, Lea B.S. (author)
- Danmarks Tekniske Universitet,Technical University of Denmark
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- Roager, Henrik M. (author)
- Danmarks Tekniske Universitet,Technical University of Denmark,Köpenhamns universitet,University of Copenhagen
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- Søndertoft, Nadja B. (author)
- Köpenhamns universitet,University of Copenhagen
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- Gøbel, Rikke J. (author)
- Köpenhamns universitet,University of Copenhagen
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- Kristensen, M. (author)
- Köpenhamns universitet,University of Copenhagen
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- Vallès-Colomer, Mireia (author)
- Katholieke Universiteit Leuven,Flanders Interuniversity Institute for Biotechnology
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- Vieira-Silva, Sara (author)
- Flanders Interuniversity Institute for Biotechnology,Katholieke Universiteit Leuven
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- Ibrügger, Sabine (author)
- Köpenhamns universitet,University of Copenhagen
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- Vendelbo Lind, Mads, 1988 (author)
- Köpenhamns universitet,University of Copenhagen
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- Mærkedahl, Rasmus B. (author)
- Köpenhamns universitet,University of Copenhagen
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- Bahl, Martin I. (author)
- Danmarks Tekniske Universitet,Technical University of Denmark
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- Madsen, M. L. (author)
- Köpenhamns universitet,University of Copenhagen
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- Havelund, Jesper (author)
- Syddansk Universitet,University of Southern Denmark
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- Falony, Gwen (author)
- Katholieke Universiteit Leuven,Flanders Interuniversity Institute for Biotechnology
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- Tetens, Inge (author)
- Köpenhamns universitet,University of Copenhagen
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- Nielsen, Trine (author)
- Köpenhamns universitet,University of Copenhagen
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- Allin, Kristine H. (author)
- Köpenhamns universitet,University of Copenhagen
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- Frandsen, Henrik L. (author)
- Danmarks Tekniske Universitet,Technical University of Denmark
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- Hartmann, Bolette (author)
- Köpenhamns universitet,University of Copenhagen
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- Holst, Jens Juul (author)
- Köpenhamns universitet,University of Copenhagen
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- Sparholt, Morten H. (author)
- Bispebjerg Hospital
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- Holck, Jesper (author)
- Danmarks Tekniske Universitet,Technical University of Denmark
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- Blennow, Andreas (author)
- Köpenhamns universitet,University of Copenhagen
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- Moll, Janne Marie (author)
- Danmarks Tekniske Universitet,Technical University of Denmark
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- Meyer, Anne S. (author)
- Danmarks Tekniske Universitet,Technical University of Denmark
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- Hoppe, Camilla (author)
- Danmarks Tekniske Universitet,Technical University of Denmark
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- Poulsen, Jørgen H. (author)
- Hvidovre Hospital
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- Carvalho, Vera (author)
- Danmarks Tekniske Universitet,Technical University of Denmark
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- Sagnelli, Domenico (author)
- Köpenhamns universitet,University of Copenhagen
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- Dalgaard, Marlene D. (author)
- Danmarks Tekniske Universitet,Technical University of Denmark
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- Christensen, Anders F. (author)
- Bispebjerg Hospital
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- Lydolph, Magnus Christian (author)
- Statens Serum Institut
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- Ross, Alastair, 1976 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Villas-Bôas, S.G.R. (author)
- University of Auckland
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- Brix, Susanne (author)
- Danmarks Tekniske Universitet,Technical University of Denmark
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- Sicheritz-Pontén, T. (author)
- Danmarks Tekniske Universitet,Technical University of Denmark
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- Buschard, Karsten (author)
- Rigshospitalet
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Linneberg, Allan (author)
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Rumessen, Jüri J. (author)
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- Ekstrøm, Claus T. (author)
- Köpenhamns universitet,University of Copenhagen
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- Ritz, Christian (author)
- Köpenhamns universitet,University of Copenhagen
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- Kristiansen, Karsten (author)
- Köpenhamns universitet,University of Copenhagen
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Nielsen, H. Bjørn (author)
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- Vestergaard, H. (author)
- Köpenhamns universitet,University of Copenhagen
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- Færgeman, Nils J. (author)
- Syddansk Universitet,University of Southern Denmark
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- Raes, Jeroen (author)
- Flanders Interuniversity Institute for Biotechnology,Katholieke Universiteit Leuven
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- Frøkiær, Hanne (author)
- Köpenhamns universitet,University of Copenhagen
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- Hansen, Torben (author)
- Köpenhamns universitet,University of Copenhagen
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- Lauritzen, L. (author)
- Köpenhamns universitet,University of Copenhagen
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- Gupta, Ramneek (author)
- Danmarks Tekniske Universitet,Technical University of Denmark
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- Licht, Tine Rask (author)
- Danmarks Tekniske Universitet,Technical University of Denmark
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- Pedersen, O. B. (author)
- Köpenhamns universitet,University of Copenhagen
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(creator_code:org_t)
- 2018-11-13
- 2018
- English.
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In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723 .- 2041-1723. ; 9:1
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https://research.cha... (primary) (free)
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https://www.nature.c...
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https://doi.org/10.1...
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Abstract
Subject headings
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- © 2018, The Author(s). Adherence to a low-gluten diet has become increasingly common in parts of the general population. However, the effects of reducing gluten-rich food items including wheat, barley and rye cereals in healthy adults are unclear. Here, we undertook a randomised, controlled, cross-over trial involving 60 middle-aged Danish adults without known disorders with two 8-week interventions comparing a low-gluten diet (2 g gluten per day) and a high-gluten diet (18 g gluten per day), separated by a washout period of at least six weeks with habitual diet (12 g gluten per day). We find that, in comparison with a high-gluten diet, a low-gluten diet induces moderate changes in the intestinal microbiome, reduces fasting and postprandial hydrogen exhalation, and leads to improvements in self-reported bloating. These observations suggest that most of the effects of a low-gluten diet in non-coeliac adults may be driven by qualitative changes in dietary fibres.
Subject headings
- LANTBRUKSVETENSKAPER -- Lantbruksvetenskap, skogsbruk och fiske -- Livsmedelsvetenskap (hsv//swe)
- AGRICULTURAL SCIENCES -- Agriculture, Forestry and Fisheries -- Food Science (hsv//eng)
- LANTBRUKSVETENSKAPER -- Veterinärmedicin -- Klinisk vetenskap (hsv//swe)
- AGRICULTURAL SCIENCES -- Veterinary Science -- Clinical Science (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Hansen, Lea B.S.
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Roager, Henrik M ...
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Søndertoft, Nadj ...
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Gøbel, Rikke J.
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Kristensen, M.
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Vallès-Colomer, ...
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show more...
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Vieira-Silva, Sa ...
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Ibrügger, Sabine
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Vendelbo Lind, M ...
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Mærkedahl, Rasmu ...
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Bahl, Martin I.
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Madsen, M. L.
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Havelund, Jesper
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Falony, Gwen
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Tetens, Inge
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Nielsen, Trine
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Allin, Kristine ...
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Frandsen, Henrik ...
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Hartmann, Bolett ...
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Holst, Jens Juul
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Sparholt, Morten ...
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Holck, Jesper
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Blennow, Andreas
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Moll, Janne Mari ...
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Meyer, Anne S.
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Hoppe, Camilla
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Poulsen, Jørgen ...
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Carvalho, Vera
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Sagnelli, Domeni ...
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Dalgaard, Marlen ...
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Christensen, And ...
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Lydolph, Magnus ...
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Ross, Alastair, ...
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Villas-Bôas, S.G ...
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Brix, Susanne
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Sicheritz-Pontén ...
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Buschard, Karste ...
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Linneberg, Allan
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Rumessen, Jüri J ...
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Ekstrøm, Claus T ...
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Ritz, Christian
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Kristiansen, Kar ...
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Nielsen, H. Bjør ...
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Vestergaard, H.
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Færgeman, Nils J ...
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Raes, Jeroen
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Frøkiær, Hanne
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Hansen, Torben
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Lauritzen, L.
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Gupta, Ramneek
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Licht, Tine Rask
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Pedersen, O. B.
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- About the subject
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- AGRICULTURAL SCIENCES
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AGRICULTURAL SCI ...
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and Agriculture Fore ...
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and Food Science
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- AGRICULTURAL SCIENCES
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AGRICULTURAL SCI ...
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and Veterinary Scien ...
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and Clinical Science
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Nutrition and Di ...
- Articles in the publication
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Nature Communica ...
- By the university
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Chalmers University of Technology