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Nanoplasmonic biosensing with focus on short-range ordered nanoholes in thin metal films
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- Jonsson, Magnus, 1981 (author)
- Chalmers tekniska högskola,Chalmers University of Technology,Chalmers, Sweden
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- Dahlin, Andreas, 1980 (author)
- Chalmers tekniska högskola,Chalmers University of Technology,Chalmers, Sweden
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- Jönsson, Peter, 1981 (author)
- Lund University,Lunds universitet,Fasta tillståndets fysik,Fysiska institutionen,Institutioner vid LTH,Lunds Tekniska Högskola,Solid State Physics,Department of Physics,Departments at LTH,Faculty of Engineering, LTH,Lund University, Sweden
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- (creator_code:org_t)
- American Vacuum Society, 2008
- 2008
- English.
- In: Biointerphases. - : American Vacuum Society. - 1559-4106 .- 1934-8630. ; 3:3, s. FD30-FD40
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- The resonance conditions for excitation of propagating surface plasmons at planar metal/dielectric interfaces and localized surface plasmons associated with metal nanostructures are both sensitive to changes in the interfacial refractive index. This has made these phenomena increasingly popular as transducer principles in label-free sensing of biomolecular recognition reactions. In this article, the authors review the recent progress in the field of nanoplasmonic bioanalytical sensing in general, but set particular focus on certain unique possibilities provided by short-range ordered nanoholes in thin metal films. Although the latter structures are formed in continuous metal films, while nanoparticles are discrete entities, these two systems display striking similarities with respect to sensing capabilities, including bulk sensitivities, and the localization of the electromagnetic fields. In contrast, periodic arrays of nanoholes formed in metal films, most known for their ability to provide wavelength-tuned enhanced transmission, show more similarities with conventional propagating surface plasmon resonance. However, common for both short-range ordered and periodic nanoholes formed in metal films is that the substrate is electrically conductive. Some of the possibilities that emerge from sensor templates that are both electrically conductive and plasmon active are discussed and illustrated using recent results on synchronized nanoplasmonic and quartz crystal microbalance with dissipation monitoring of supported lipid bilayer formation and subsequent biomolecular recognition reactions. Besides the fact that this combination of techniques provides an independent measure of biomolecular structural changes, it is also shown to contribute with a general means to quantify the response from nanoplasmonic sensors in terms of bound molecular mass. c 2008 American Vacuum Society.
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Annan teknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Other Engineering and Technologies (hsv//eng)
- NATURVETENSKAP -- Fysik -- Den kondenserade materiens fysik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Condensed Matter Physics (hsv//eng)
Keyword
- QUANTITATIVE INTERPRETATION
- NANOSCALE OPTICAL BIOSENSOR
- LIPID-BILAYER FORMATION
- SURFACE-PLASMON RESONANCE
- GOLD-NANOPARTICLE
- SENSOR
- ENHANCED
- QUARTZ-CRYSTAL MICROBALANCE
- TIME-DOMAIN METHOD
- SILVER
- NANOPARTICLES
- BIOMOLECULAR INTERACTIONS
- RAMAN-SCATTERING
Publication and Content Type
- art (subject category)
- ref (subject category)
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