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Optical studies on complexes between DNA and pseudoisocyanine

Nordén, Bengt, 1945 (author)
Tjerneld, F. (author)
Elsevier BV, 1976
1976
English.
In: Biophysical Chemistry. - : Elsevier BV. - 1873-4200 .- 0301-4622. ; 6:1, s. 31-45
  • Journal article (peer-reviewed)
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  • Linear dichroism (LD) results when pseudoisocyanine = PIC (1, 1-diethyl-2,2'-cyanine iodide) binds to flow-oriented DNA. LD may be used to follow the complexation both stoichiometrically and structurally, since when specified to unit complex concentration LD provides a measure of the average orientation of the absorbing transition dipole.Two different types of complexes can be distinguished: I. One strong, ionic-strength insensitive complex with monomeric PIC with an orientation indicating intercalation. II. Several weaker complexes of electrostatic nature (only observed at I

Subject headings

NATURVETENSKAP  -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)

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