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Precontrolled Align...
Precontrolled Alignment of Graphite Nanoplatelets in Polymeric Composites Prevents Bacterial Attachment
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- Pandit, Santosh, 1987 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Gaska, Karolina, 1986 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Mokkapati, Venkata Raghavendra Subrahmanya Sar, 1981 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Celauro, Emanuele, 1980 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Derouiche, Abderahmane, 1980 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Forsberg, Sven (author)
- 2D fab AB
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Svensson, Magnus (author)
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- Kádár, Roland, 1982 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Mijakovic, Ivan, 1975 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
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(creator_code:org_t)
- 2020-01-09
- 2020
- English.
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In: Small. - : Wiley. - 1613-6810 .- 1613-6829. ; 16:5
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Abstract
Subject headings
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- Graphene coatings composed of vertical spikes are shown to mitigate bacterial attachment. Such coatings present hydrophobic edges of graphene, which penetrate the lipid bilayers causing physical disruption of bacterial cells. However, manufacturing of such surfaces on a scale required for antibacterial applications is currently not feasible. This study explores whether graphite can be used as a cheaper alternative to graphene coatings. To examine this, composites of graphite nanoplatelets (GNP) and low-density polyethylene (LDPE) are extruded in controlled conditions to obtain controlled orientation of GNP flakes within the polymer matrix. Flakes are exposed by etching the surface of GNP–LDPE nanocomposites and antibacterial activity is evaluated. GNP nanoflakes on the extruded samples interact with bacterial cell membranes, physically damaging the cells. Bactericidal activity is observed dependent on orientation and nanoflakes density. Composites with high density of GNP (≥15%) present two key advantages: i) they decrease bacterial viability by a factor of 99.9999%, which is 10 000-fold improvement on the current benchmark, and ii) prevent bacterial colonization, thus drastically reducing the numbers of dead cells on the surface. The latter is a key advantage for longer-term biomedical applications, since these surfaces will not have to be cleaned or replaced for longer periods.
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Materialteknik -- Textil-, gummi- och polymermaterial (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Materials Engineering -- Textile, Rubber and Polymeric Materials (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Biomedicinsk laboratorievetenskap/teknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Biomedical Laboratory Science/Technology (hsv//eng)
Keyword
- Composite materials
- graphite nanoplatelets
- Adhesion
- low density polyethylene
Publication and Content Type
- art (subject category)
- ref (subject category)
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Pandit, Santosh, ...
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Gaska, Karolina, ...
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Mokkapati, Venka ...
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Celauro, Emanuel ...
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Derouiche, Abder ...
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Forsberg, Sven
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Svensson, Magnus
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Kádár, Roland, 1 ...
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Mijakovic, Ivan, ...
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- About the subject
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- ENGINEERING AND TECHNOLOGY
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ENGINEERING AND ...
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and Medical Engineer ...
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- ENGINEERING AND TECHNOLOGY
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ENGINEERING AND ...
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and Materials Engine ...
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and Textile Rubber a ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Medical Biotechn ...
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and Biomedical Labor ...
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Small
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Chalmers University of Technology