Patterned Stimulation of Peripheral Nerves Produces Natural Sensations With Regards to Location but Not Quality

Ortiz Catalan, Max Jair, 1982 (author): Chalmers tekniska högskola,Chalmers University of Technology

Wessberg, Johan, 1962 (author): Göteborgs universitet,University of Gothenburg

Mastinu, Enzo, 1987 (author): Chalmers tekniska högskola,Chalmers University of Technology

Naber, Autumn, 1988 (author): Chalmers tekniska högskola,Chalmers University of Technology

Brånemark, Rickard, 1960 (author): Göteborgs universitet,University of Gothenburg

(creator_code:org_t)

2019
2019
English.
In: IEEE Transactions on Medical Robotics and Bionics. - 2576-3202. ; 1:3, s. 199-203

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Abstract Subject headings

Sensory feedback is crucial for dexterous manipulation and sense of ownership. Electrical stimulation of severed afferent fibers due to an amputation elicits referred sensations in the missing limb. However, these sensations are commonly reported with a concurrent “electric” or “tingling” character (paresthesia). In this paper, we examined the effect of modulating different pulse parameters on the quality of perceived sensations. Three subjects with above-elbow amputation were implanted with cuff electrodes and stimulated with a train of pulses modulated in either amplitude, width, or frequency (“patterned stimulation”). Pulses were shaped using a slower carrier wave or via quasi-random generation. Subjects were asked to evaluate the natural quality of the resulting sensations using a numeric rating scale. We found that the location of the percepts was distally referred and somatotopically congruent, but their quality remained largely perceived as artificial despite employing patterned modulation. Sensations perceived as arising from the missing limb are intuitive and natural with respect to their location and, therefore, useful for functional restoration. However, our results indicate that sensory transformation from paresthesia to natural qualia seems to require more than patterned stimulation.

TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Annan medicinteknik (hsv//swe)
ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Other Medical Engineering (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk apparatteknik (hsv//swe)
ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Equipment Engineering (hsv//eng)
TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk material- och protesteknik (hsv//swe)
ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Materials (hsv//eng)

By the author/editor: Ortiz Catalan, M ...; Wessberg, Johan, ...; Mastinu, Enzo, 1 ...; Naber, Autumn, 1 ...; Brånemark, Ricka ...

About the subject

ENGINEERING AND TECHNOLOGY: ENGINEERING AND ...; and Medical Engineer ...; and Other Medical En ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Neurosciences

ENGINEERING AND TECHNOLOGY: ENGINEERING AND ...; and Medical Engineer ...; and Medical Equipmen ...

ENGINEERING AND TECHNOLOGY: ENGINEERING AND ...; and Medical Engineer ...; and Medical Material ...

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