Search: onr:"swepub:oai:research.chalmers.se:76fadecf-d5c5-4356-93e9-910f7c112a3c" >
Does osteoporosis t...
Abstract
Subject headings
Close
- Ten-year fracture risk assessment with the fracture risk assessment system (FRAX) is increasingly used to guide treatment decisions. Osteoporosis pharmacotherapy reduces fracture risk, but the effect is greater than can be explained from the increase in bone mineral density (BMD). Whether this invalidates fracture predictions with FRAX is uncertain. A total of 35,764 women (age ≥50 years) and baseline BMD testing (1996–2007) had FRAX probabilities retroactively calculated. A provincial pharmacy database was used to identify osteoporosis medication use. Women were categorized as untreated, current high adherence users [medication possession ratio (MPR) ≥0.80 in the year after BMD testing], current low adherence users (MPR
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Keyword
- epidemiology
- Canada
- diagnosis
- epidemiology
- Aged
- Area Under Curve
- diagnosis
- Risk Assessment
- Osteoporotic Fractures
- ROC Curve
- epidemiology
- Humans
- Proportional Hazards Models
- therapy
- Middle Aged
- Femoral Neck Fractures
- methods
- Female
- Cohort Studies
- Reproducibility of Results
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database