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Sealing of Submicrometer Wells by a Shear-Driven Lipid Bilayer
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- Jönsson, Peter, 1981 (author)
- Chalmers tekniska högskola,Chalmers University of Technology,Department of Applied Physics, Chalmers University of Technology, SE-41296 Gothenburg, Sweden
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- Jonsson, Magnus, 1981 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Höök, Fredrik, 1966 (author)
- Chalmers tekniska högskola,Chalmers University of Technology,Department of Applied Physics, Chalmers University of Technology, SE-41296 Gothenburg, Sweden
- (creator_code:org_t)
- 2010-04-20
- 2010
- English.
- In: Nano Letters. - : American Chemical Society (ACS). - 1530-6992 .- 1530-6984. ; 10:5, s. 1900-1906
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- A supported lipid bilayer (SLB) was formed in a microfluidic channel by vesicle fusion. The SLB, formed on a flat part of the surface, was driven by the shear forces of a bulk flow above the SLB to a part of the surface with embedded submicrometer wells. When using a bulk solution with a pH of 9.5 the advancing lipid bilayer sealed the wells, creating free-spanning membranes, whereas at a pH of 8.0 the SLB instead followed the contour of the wells.
Subject headings
- NATURVETENSKAP -- Fysik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences (hsv//eng)
- NATURVETENSKAP -- Biologi -- Biofysik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biophysics (hsv//eng)
Keyword
- microfluidics
- SILICON
- CHANNELS
- molecule encapsulation
- MONOLAYERS
- SUPPORTED PHOSPHOLIPID-BILAYERS
- MEMBRANES
- KINETICS
- Spreading lipid bilayers
- HYDROPHILIC SURFACES
- BIOSENSOR
- NANOPORE ARRAYS
- DIFFUSION
- nanostructures
- black lipid membranes
Publication and Content Type
- art (subject category)
- ref (subject category)
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