Resonant neutral particle emission in collisions of electrons with protonated peptides with disulfide bonds at high energies

• Electron-ion collisions were studied for various protonated peptide monocations with disulfide bonds, using an electrostatic storage-ring equipped with a merged-electron-beam device. Resonant neutral particle emissions at the energies of 6-7 eV were observed, as well as a rise towards zero-energy, which are typical electron-capture dissociation profiles. The presence of disulfide (S-S) bonds tends to enhance the resonant bump heights. Chemical nature of the amino-acid residues adjacent to cysteines appears to correlate with the bump strength. Molecular-dynamical simulations help clarify the role of molecular vibration modes in the electron-capture dissociation process. (C) 2011 Elsevier B. V. All rights reserved.

Subject headings

NATURVETENSKAP  -- Kemi -- Fysikalisk kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences -- Physical Chemistry (hsv//eng)

Keyword

gas-phase

ion/ion reactions

polypeptide ions

hydrogen-atom adducts

electrostatic storage-ring

capture

attachment

dissociation

amide bond

peptides

model peptide

helical

Publication and Content Type

art (subject category)

ref (subject category)