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Search: onr:"swepub:oai:research.chalmers.se:90cb3866-834e-48c0-b13d-56a57c9a31bb" > Evaluating an Inter...

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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004792naa a2200529 4500
001oai:research.chalmers.se:90cb3866-834e-48c0-b13d-56a57c9a31bb
003SwePub
008210414s2021 | |||||||||||000 ||eng|
024a https://research.chalmers.se/publication/5232932 URI
024a https://doi.org/10.1093/jn/nxaa3472 DOI
040 a (SwePub)cth
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
100a Donin, Angela S.u University of London4 aut
2451 0a Evaluating an Intervention to Increase Cereal Fiber Intake in Children: A Randomized Controlled Feasibility Trial
264 1b Elsevier BV,c 2021
338 a electronic2 rdacarrier
520 a BACKGROUND: Observational studies have shown that higher cereal fiber intake is associated with reduced type 2 diabetes risk. However, it remains uncertain whether this association is causal. OBJECTIVE: This study evaluated the feasibility of an intervention to increase cereal fiber intake in children using breakfast cereals. METHODS: The study was a 2-arm parallel group randomized controlled trial in 9-10-y-old children, who received free supplies of high-fiber breakfast cereals (>3.5 g/portion) or low-fiber breakfast cereals (<1.0 g/portion) to eat daily for 1 mo with behavioral support to promote adherence. Children provided baseline and 1-mo fasting blood samples, physical measurements, and 24-h dietary recalls. The primary outcome was the group difference in change in plasma total alkylresorcinol (AR) concentration; secondary outcomes were group differences in nutrient intakes and adiposity indices. Analyses (complete case and multiple imputation) were conducted by regressing the final AR concentration on baseline AR in models adjusted for sex, ethnicity, age, and school (random effect). RESULTS: Two-hundred seventy-two children were randomly assigned (137 receiving a low-fiber and 135 a high-fiber diet) and 193 (71%) provided fasting blood samples at baseline and follow-up. Among randomized participants, median (IQR) of baseline AR was 43.1 (24.6-85.5) nmol/L and of cereal fiber intake was 4.5 (2.7-6.4) g; 87% of participants reported consuming the cereal on most or all days. Compared with changes in the low-fiber group, the high-fiber group had greater increases in AR (40.7 nmol/L; 95% CI: 21.7, 59.8 nmol/L, P < 0.0001) and in reported cereal fiber intake (2.9g/d; 95% CI: 2.0, 3.7 g; P < 0.0001). There were no appreciable differences in other secondary outcomes. CONCLUSIONS: We have developed a simple and acceptable nutritional intervention that increases markers of daily cereal fiber intake in children. This intervention could be used to test whether increases in cereal fiber intake in children might reduce insulin resistance. This trial was registered at www.isrctn.com as ISRCTN33260236.
650 7a LANTBRUKSVETENSKAPERx Lantbruksvetenskap, skogsbruk och fiskex Livsmedelsvetenskap0 (SwePub)401032 hsv//swe
650 7a AGRICULTURAL SCIENCESx Agriculture, Forestry and Fisheriesx Food Science0 (SwePub)401032 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Näringslära0 (SwePub)303042 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Nutrition and Dietetics0 (SwePub)303042 hsv//eng
653 a children
653 a type 2 diabetes risk
653 a Cereal fiber
653 a feasibility trial
653 a dietary intervention
700a Nightingale, Claire M.u University of London4 aut
700a Perkin, Michael R.u University of London4 aut
700a Ussher, Michaelu University of Stirling,University of London4 aut
700a Jebb, Susan A.u University Of Oxford4 aut
700a Landberg, Rikard,d 1981u Chalmers tekniska högskola,Chalmers University of Technology4 aut0 (Swepub:cth)riklan
700a Welsh, Paulu University of Glasgow4 aut
700a Sattar, Naveedu University of Glasgow4 aut
700a Adab, Peymaneu University of Birmingham4 aut
700a Owen, Chris G.u University of London4 aut
700a Rudnicka, Alicja R.u University of London4 aut
700a Cook, Derek G.u University of London4 aut
700a Whincup, Peter H.u University of London4 aut
710a University of Londonb University of Stirling4 org
773t Journal of Nutritiond : Elsevier BVg 151:2, s. 379-386q 151:2<379-386x 1541-6100x 0022-3166
856u https://research.chalmers.se/publication/523293/file/523293_Fulltext.pdfx primaryx freey FULLTEXT
856u https://academic.oup.com/jn/article-pdf/151/2/379/36154469/nxaa347.pdf
8564 8u https://research.chalmers.se/publication/523293
8564 8u https://doi.org/10.1093/jn/nxaa347

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