Search: onr:"swepub:oai:research.chalmers.se:aa0e721b-fe0b-4e5d-9b06-be4136ee538d" >
Current progress in...
-
Westman, Johan,1983Chalmers tekniska högskola,Chalmers University of Technology
(author)
Current progress in high cell density yeast bioprocesses for bioethanol production
- Article/chapterEnglish2015
Publisher, publication year, extent ...
-
2015-07-24
-
Wiley,2015
-
electronicrdacarrier
Numbers
-
LIBRIS-ID:oai:research.chalmers.se:aa0e721b-fe0b-4e5d-9b06-be4136ee538d
-
https://research.chalmers.se/publication/220931URI
-
https://doi.org/10.1002/biot.201400581DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:for swepub-publicationtype
-
Subject category:ref swepub-contenttype
Notes
-
High capital costs and low reaction rates are major challenges for establishment of fermentation-based production systems in the bioeconomy. Using high cell density cultures is an efficient way to increase the volumetric productivity of fermentation processes, thereby enabling faster and more robust processes and use of smaller reactors. In this review, we summarize recent progress in the application of high cell density yeast bioprocesses for first and second generation bioethanol production. High biomass concentrations obtained by retention of yeast cells in the reactor enables easier cell reuse, simplified product recovery and higher dilution rates in continuous processes. High local cell density cultures, in the form of encapsulated or strongly flocculating yeast, furthermore obtain increased tolerance to convertible fermentation inhibitors and utilize glucose and other sugars simultaneously, thereby overcoming two additional hurdles for second generation bioethanol production. These effects are caused by local concentration gradients due to diffusion limitations and conversion of inhibitors and sugars by the cells, which lead to low local concentrations of inhibitors and glucose. Quorum sensing may also contribute to the increased stress tolerance. Recent developments indicate that high cell density methodology, with emphasis on high local cell density, offers significant advantages for sustainable second generation bioethanol production.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Franzén, Carl Johan,1966Chalmers tekniska högskola,Chalmers University of Technology(Swepub:cth)franzen
(author)
-
Chalmers tekniska högskola
(creator_code:org_t)
Related titles
-
In:Biotechnology journal: Wiley10:8, s. 1185-11951860-67681860-7314
Internet link
Find in a library
To the university's database