Serum concentrations of VEGF and b-FGF in renal cell, prostate and urinary bladder carcinomas.

• Sixty nine patients with urogenital cancers (renal, bladder and prostate cancer) were studied to determine whether the serum concentrations of Vascular Endothelial Growth Factor (VEGF) and basic Fibroblast Growth Factor (b-FGF) reflected the status of the patients and/or the prognosis of the disease. Of the patients included in this study, renal cell carcinoma patients expressed the highest levels of VEGF indicating that these tumours are more VEGF dependent. The values of b-FGF could be considered normal in all three malignancies. No correlation was observed between the expression of VEGF and b-FGF, nor between VEGF and b-FGF and patients survival.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Keyword

Middle Aged

80 and over

blood

Fibroblast Growth Factor 2

Kidney Neoplasms

Aged

blood

Endothelial Growth Factors

Adult

blood

Prostatic Neoplasms

Female

Vascular Endothelial Growth Factors

Vascular Endothelial Growth Factor A

Carcinoma

Lymphokines

Male

blood

Humans

Renal Cell

Urinary Bladder Neoplasms

Enzyme-Linked Immunosorbent Assay

Aged

blood

blood

blood

Publication and Content Type

art (subject category)

ref (subject category)