onr:"swepub:oai:research.chalmers.se:cd3f0233-ef02-489e-8c76-d9d7b8b065b3"
Search: onr:"swepub:oai:research.chalmers.se:cd3f0233-ef02-489e-8c76-d9d7b8b065b3" > Echogenecity of the...
- 1 of 1
- Previous record
- Next record
- To hitlist
Echogenecity of the carotid intima-media complex is related to cardiovascular risk factors, dyslipidemia, oxidative stress and inflammation The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study
-
- Andersson, J. (author)
- Uppsala universitet,Institutionen för medicinska vetenskaper
-
- Sundström, Johan (author)
- Uppsala universitet,Institutionen för medicinska vetenskaper
-
- Gustavsson, Tomas, 1954 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
- show more...
- show less...
- (creator_code:org_t)
- Elsevier BV, 2009
- 2009
- English.
- In: Atherosclerosis. - : Elsevier BV. - 1879-1484 .- 0021-9150. ; 204:2, s. 612-618
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Background: Increased carotid artery intima-media thickness (IMT), measured by ultrasound, is related to an increased risk of cardiovascular disease. Since presence of echolucent plaques increases the risk further, we investigated if echogenecity of the carotid intima-media complex is related to markers of cardiovascular risk. Our aim was therefore to investigate if intima-media echogenecity is related to cardiovascular risk factors, or to markers of inflammation and oxidation in an exploratory investigation. Methods: The PIVUS cohort study is an observational study of 1016 (509 women and 507 men) randomly chosen individuals aged 70 living in Uppsala, Sweden. Carotid artery ultrasound measurements were performed. IMT and the grey scale median (GSM) value were calculated in the intima-media complex (IM-GSM) in the far wall of the common carotid artery. Traditional risk factors were evaluated together with indices of oxidative stress and inflammation. Results: In the multiple regression analysis, HDL-cholesterol, body mass index, conjugated diens, glutathione, e-selectin and TNF alfa were significantly related to IM-GSM. IMT was independently related to blood pressure, smoking and body mass index. Conclusion: The echolucency of the carotid intima-media was related to several cardiovascular risk factors not related to IMT, such as dyslipidemia, oxidative stress and inflammation. Since the echogenecity of the carotid intima-media complex was related to different risk factors compared to carotid IMT, it is worthwhile to further explore the usefulness of this new marker of the vascular wall. (C) 2009 Published by Elsevier Ireland Ltd.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- artery-disease
- myocardial-infarction
- Carotid artery
- Lipids
- low-density-lipoprotein
- progression
- coronary-heart-disease
- prediction
- plaques
- Atherosclerosis
- Oxidation
- atherosclerosis risk
- Risk factor
- c-reactive protein
- thickness
- Echogenecity
- Ultrasound
- MEDICINE
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
- Atherosclerosis (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Andersson, J.
- Sundström, Johan
- Gustavsson, Toma ...
- Hulthe, Johannes ...
- Elmgren, A.
- Zilmer, K.
- show more...
- Zilmer, M.
- Lind, Lars
- show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Cardiac and Card ...
- Articles in the publication
- Atherosclerosis
- By the university
- Chalmers University of Technology
- Uppsala University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
