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Similar is not the ...
Similar is not the same: Differences in the function of the (hemi-)cellulolytic regulator XlnR (Xlr1/Xyr1) in filamentous fungi
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- Klaubauf, Sylvia, 1981 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
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Narang, Hari Mander (author)
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Post, Harm (author)
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Zhou, Miaomiao (author)
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Brunner, Kurt (author)
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Mach-Aigner, Astrid R. (author)
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Mach, Robert L. (author)
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Heck, Albert J.R. (author)
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Altelaar, A.F. Maarten (author)
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Vries, Ronald P. de (author)
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(creator_code:org_t)
- 2014
- 2014
- English.
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In: Fungal Genetics and Biology. - 1096-0937 .- 1087-1845. ; 72, s. 73-81
- Related links:
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https://research.cha...
Abstract
Subject headings
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- The transcriptional activator XlnR (Xlr1/Xyr1) is a major regulator in fungal xylan and cellulose degradation as well as in the utilization of d-xylose via the pentose catabolic pathway. XlnR homologs are commonly found in filamentous ascomycetes and often assumed to have the same function in different fungi. However, a comparison of the saprobe Aspergillus niger and the plant pathogen Magnaporthe oryzae showed different phenotypes for deletion strains of XlnR. In this study wild type and xlnR/xlr1/xyr1 mutants of five fungi were compared: Fusarium graminearum, M. oryzae, Trichoderma reesei, A. niger and Aspergillus nidulans. Growth profiling on relevant substrates and a detailed analysis of the secretome as well as extracellular enzyme activities demonstrated a common role of this regulator in activating genes encoding the main xylanolytic enzymes. However, large differences were found in the set of genes that is controlled by XlnR in the different species, resulting in the production of different extracellular enzyme spectra by these fungi. This comparison emphasizes the functional diversity of a fine-tuned (hemi-)cellulolytic regulatory system in filamentous fungi, which might be related to the adaptation of fungi to their specific biotopes. Data are available via ProteomeXchange with identifier PXD001190.
Subject headings
- NATURVETENSKAP -- Biologi -- Mikrobiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Microbiology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
Keyword
- Magnaporthe oryzae
- Xylan degradation
- Trichoderma reesei
- XlnR
- Aspergillus
- Fusarium graminearum
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Klaubauf, Sylvia ...
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Narang, Hari Man ...
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Post, Harm
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Zhou, Miaomiao
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Brunner, Kurt
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Mach-Aigner, Ast ...
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show more...
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Mach, Robert L.
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Heck, Albert J.R ...
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Altelaar, A.F. M ...
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Vries, Ronald P. ...
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show less...
- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Microbiology
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Genetics
- Articles in the publication
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Fungal Genetics ...
- By the university
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Chalmers University of Technology