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- Wang, JinpengNanjing Tech University (author)
Metabolic engineering for increased lipid accumulation in Yarrowia lipolytica – A Review
- Article/chapterEnglish2020
Publisher, publication year, extent ...
- Elsevier BV,2020
Numbers
- LIBRIS-ID:oai:research.chalmers.se:de86647b-8ba9-44e8-8b23-d72677cb73f8
- https://research.chalmers.se/publication/518390URI
- https://doi.org/10.1016/j.biortech.2020.123707DOI
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- Language:English
- Summary in:English
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- Current energy security and climate change policies encourage the development and utilization of bioenergy. Oleaginous yeasts provide a particularly attractive platform for the sustainable production of biofuels and industrial chemicals due to their ability to accumulate high amounts of lipids. In particular, microbial lipids in the form of triacylglycerides (TAGs) produced from renewable feedstocks have attracted considerable attention because they can be directly used in the production of biodiesel and oleochemicals analogous to petrochemicals. As an oleaginous yeast that is generally regarded as safe, Yarrowia lipolytica has been extensively studied, with large amounts of data on its lipid metabolism, genetic tools, and genome sequencing and annotation. In this review, we highlight the newest strategies for increasing lipid accumulation using metabolic engineering and summarize the research advances on the overaccumulation of lipids in Y. lipolytica. Finally, perspectives for future engineering approaches are proposed.
Subject headings and genre
- SAMHÄLLSVETENSKAP Annan samhällsvetenskap Tvärvetenskapliga studier inom samhällsvetenskap hsv//swe
- SOCIAL SCIENCES Other Social Sciences Social Sciences Interdisciplinary hsv//eng
- LANTBRUKSVETENSKAPER Annan lantbruksvetenskap Förnyelsebar bioenergi hsv//swe
- AGRICULTURAL SCIENCES Other Agricultural Sciences Renewable Bioenergy Research hsv//eng
- TEKNIK OCH TEKNOLOGIER Naturresursteknik Energisystem hsv//swe
- ENGINEERING AND TECHNOLOGY Environmental Engineering Energy Systems hsv//eng
- Biodiesel
- Triacylglycerides
- Yarrowia lipolytica
- Lipid accumulation
- Metabolic engineering
Added entries (persons, corporate bodies, meetings, titles ...)
- Ledesma-Amaro, R.Imperial College of Science, Technology and Medicine (author)
- Wei, YongjunZhengzhou University (author)
- Ji, Boyang,1983Danmarks Tekniske Universitet,Technical University of Denmark,Chalmers tekniska högskola,Chalmers University of Technology(Swepub:cth)bojand (author)
- Ji, Xiao JunNanjing Tech University (author)
- Nanjing Tech UniversityImperial College of Science, Technology and Medicine (creator_code:org_t)
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- In:Bioresource Technology: Elsevier BV3130960-85241873-2976
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