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Challenges of small...
Challenges of small RNA technology
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- Singh, Ravi Kumar (author)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för växtbiologi,Department of Plant Biology
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(creator_code:org_t)
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- ISBN 9780128171127
- 2020
- 2020
- English.
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In: Plant Small RNA : Biogenesis, Regulation and Application. - 9780128171127 ; , s. 545-565
- Related links:
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https://res.slu.se/i...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Plant small RNAs are largely non-coding, regulatory RNAs that act with a sequence-specific binding capacity to regulate target gene expression, either before transcription, a process called transcriptional gene silencing (TGS), or after transcription, a process called post-transcriptional gene silencing (PTGS) or RNA interference (RNAi), in general. Emerging evidence from high-throughput sequencing technologies leads us in characterizing several categories and groups of small RNAs. They play essential roles in complex biological processes under various physiological conditions. Small RNA-mediated gene silencing has been proven as a promising and powerful genetic tool for the improvement of crop plants and agriculture. It has emerged as a means to probe the function of a gene of interest on a whole-genome scale. Parallel to the enormous potential and applications, this technology has met with several new challenges, such as the off-target effects, delivery of optimum and sufficient small RNAs at the targeted cells, its measure for persistence in the environment, and several ethical issues.
Subject headings
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
Publication and Content Type
- ref (subject category)
- kap (subject category)
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