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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003559naa a2200361 4500
001oai:slubar.slu.se:99881
003SwePub
008240410s2019 | |||||||||||000 ||eng|
024a https://res.slu.se/id/publ/998812 URI
024a https://doi.org/10.1038/s41598-019-42741-62 DOI
040 a (SwePub)slu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Thaduri, Srinivasu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för ekologi,Department of Ecology4 aut0 (Swepub:slu)93604
2451 0a Disentangling host-parasite-pathogen interactions in a varroa-resistant honeybee population reveals virus tolerance as an independent, naturally adapted survival mechanism
264 c 2019-04-17
264 1b Springer Science and Business Media LLC,c 2019
264 1b Nature Publishing Group: Open Access Journals - Option C / Nature Publishing Group,c 2024
520 a The ectoparasitic mite, Varroa destructor, is unarguably the leading cause of honeybee (Apis mellifera) mortality worldwide through its role as a vector for lethal viruses, in particular, strains of the Deformed wing virus (DWV) and Acute bee paralysis virus (ABPV) complexes. This multi-level system of host-parasite-pathogen interactions makes it difficult to investigate effects of either the mite or the virus on natural host survival. The aim of this study was to remove confounding effects of varroa to examine the role of virus susceptibility in the enhanced survival of a naturally adapted Swedish mite-resistant (MR) honeybee population, relative to mite-susceptible (MS) honeybees. Caged adult bees and laboratory reared larvae, from varroa-free colonies, were inoculated with DWV and ABPV in a series of feeding infection experiments, while control groups received virus-free food. Virus infections were monitored using RT-qPCR assays in individuals sampled over a time course. In both adults and larvae the DWV and ABPV infection dynamics were nearly identical between MR and MS groups, but MS adults suffered significantly higher mortality than MR adults. Results suggest virus tolerance, rather than reduced susceptibility or virus resistance, is an important component of the natural survival of this honeybee population.
650 7a NATURVETENSKAPx Biologix Ekologi0 (SwePub)106112 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciencesx Ecology0 (SwePub)106112 hsv//eng
700a Stephan, Jörgu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för ekologi,Department of Ecology4 aut0 (Swepub:slu)47250
700a Rodrigues De Miranda, Joachimu Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för ekologi,Department of Ecology4 aut0 (Swepub:slu)50450
700a Locke Grandér, Barbarau Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för ekologi,Department of Ecology4 aut0 (Swepub:slu)50731
710a Sveriges lantbruksuniversitetb Institutionen för ekologi4 org
710a Sveriges lantbruksuniversitet
773t Scientific Reportsd : Springer Science and Business Media LLCg 9q 9x 2045-2322
856u https://pub.epsilon.slu.se/id/eprint/16114/contentsx primaryx Raw objectx freey FULLTEXT
856u https://www.nature.com/articles/s41598-019-42741-6.pdf
8564 8u https://res.slu.se/id/publ/99881
8564 8u https://doi.org/10.1038/s41598-019-42741-6

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