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1.	Milne, RL, et al. (author) Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer 2017 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 49:12, s. 1767-1778 Journal article (peer-reviewed)
2.	Michailidou, K, et al. (author) Association analysis identifies 65 new breast cancer risk loci 2017 In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 551:7678, s. 92- Journal article (peer-reviewed)
3.	Arouca, AB, et al. (author) Diet as a moderator in the association of sedentary behaviors with inflammatory biomarkers among adolescents in the HELENA study 2019 In: European journal of nutrition. - : Springer Science and Business Media LLC. - 1436-6215 .- 1436-6207. ; 58:5, s. 2051-2065 Journal article (peer-reviewed)
4.	Collese, TS, et al. (author) How do energy balance-related behaviors cluster in adolescents? 2019 In: International journal of public health. - : Springer Science and Business Media LLC. - 1661-8564 .- 1661-8556. ; 64:2, s. 195-208 Journal article (peer-reviewed)
5.	Gimenez-Legarre, N, et al. (author) Dietary Patterns and Their Relationship With the Perceptions of Healthy Eating in European Adolescents: The HELENA Study 2019 In: Journal of the American College of Nutrition. - : Informa UK Limited. - 1541-1087 .- 0731-5724. ; 38:8, s. 703-713 Journal article (peer-reviewed)
6.	Santos, TSS, et al. (author) Measuring nutritional knowledge using Item Response Theory and its validity in European adolescents 2019 In: Public health nutrition. - 1475-2727. ; 22:3, s. 419-430 Journal article (peer-reviewed)
7.	Escala-Garcia, M, et al. (author) Genome-wide association study of germline variants and breast cancer-specific mortality 2019 In: British journal of cancer. - : Springer Science and Business Media LLC. - 1532-1827 .- 0007-0920. ; 120:6, s. 647-657 Journal article (peer-reviewed)
8.	Phelan, CM, et al. (author) Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer 2017 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 49:5, s. 680-691 Journal article (peer-reviewed)
9.	Kar, SP, et al. (author) Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types 2016 In: Cancer discovery. - : AMER ASSOC CANCER RESEARCH. - 2159-8290 .- 2159-8274. ; 6:9, s. 1052-1067 Journal article (peer-reviewed)
10.	Barregård, Lars, 1948, et al. (author) Human and Methodological Sources of Variability in the Measurement of Urinary 8-Oxo-7,8-dihydro-2 '-deoxyguanosine 2013 In: Antioxidants and Redox Signaling. - : Mary Ann Liebert Inc. - 1523-0864 .- 1557-7716. ; 18:18, s. 2377-2391 Journal article (peer-reviewed)abstract Aims: Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) is a widely used biomarker of oxidative stress. However, variability between chromatographic and ELISA methods hampers interpretation of data, and this variability may increase should urine composition differ between individuals, leading to assay interference. Furthermore, optimal urine sampling conditions are not well defined. We performed inter-laboratory comparisons of 8-oxodG measurement between mass spectrometric-, electrochemical- and ELISA-based methods, using common within-technique calibrants to analyze 8-oxodG-spiked phosphate-buffered saline and urine samples. We also investigated human subject- and sample collection-related variables, as potential sources of variability. Results: Chromatographic assays showed high agreement across urines from different subjects, whereas ELISAs showed far more inter-laboratory variation and generally overestimated levels, compared to the chromatographic assays. Excretion rates in timed 'spot' samples showed strong correlations with 24 h excretion (the 'gold' standard) of urinary 8-oxodG (r(p) 0.67-0.90), although the associations were weaker for 8-oxodG adjusted for creatinine or specific gravity (SG). The within-individual excretion of 8-oxodG varied only moderately between days (CV 17% for 24 h excretion and 20% for first void, creatinine-corrected samples). Innovation: This is the first comprehensive study of both human and methodological factors influencing 8-oxodG measurement, providing key information for future studies with this important biomarker. Conclusion: ELISA variability is greater than chromatographic assay variability, and cannot determine absolute levels of 8-oxodG. Use of standardized calibrants greatly improves intra-technique agreement and, for the chromatographic assays, importantly allows integration of results for pooled analyses. If 24 h samples are not feasible, creatinine- or SG-adjusted first morning samples are recommended.

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Type of publication: journal article (50); conference paper (16); reports (2); book (2); research review (1)

Type of content: peer-reviewed (58); other academic/artistic (13)

Author/Editor: Olsson, Håkan (7); Dennis, J (5); Peterlongo, P (5); Anton-Culver, H (5); Giles, GG (5); Milne, RL (5); show more...; Wolk, Alicja (5); Orr, N (5); Southey, MC (5); Hamann, U (5); Fasching, PA (5); Ekici, AB (5); Beckmann, MW (5); Couch, FJ (5); Gutierrez, A. (4); Ortega, FB (4); Merino, G. (4); Hakansson, N. (4); Benitez, J. (4); Brenner, H (4); Vardavas, C (4); Garcia, E. (4); Wang, Q. (4); Blomqvist, C (4); Hall, P (4); Czene, K (4); Lindblom, A (4); Wolk, A (4); Ferrari, M (4); Sylven, C (4); Larsson, M (4); Bolla, MK (4); Gonzalez-Neira, A (4); Hopper, JL (4); Teo, SH (4); Brauch, H (4); Dunning, AM (4); Andrulis, IL (4); Knight, JA (4); Glendon, G (4); Schmidt, MK (4); Wu, AH (4); Cox, A (4); Radice, P (4); Manoukian, S (4); Burwinkel, B (4); Guenel, P (4); Bojesen, SE (4); Nordestgaard, BG (4); Arndt, V (4); show less...

University: Karolinska Institutet (40); Lund University (22); University of Gothenburg (20); Uppsala University (9); Örebro University (3); Umeå University (2); show more...; Royal Institute of Technology (2); Stockholm University (2); Linköping University (1); Jönköping University (1); Mid Sweden University (1); Chalmers University of Technology (1); Högskolan Dalarna (1); show less...

Language: English (65); Swedish (6)

Research subject (UKÄ/SCB): Medical and Health Sciences (33); Social Sciences (11); Natural sciences (4); Engineering and Technology (2)

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