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  • Nilsson, Emma A, et al. (author)
  • Epigenetic alterations in human liver from subjects with type 2 diabetes in parallel with reduced folate levels.
  • 2015
  • In: Journal of Clinical Endocrinology and Metabolism. - : The Endocrine Society. - 1945-7197 .- 0021-972X. ; 100:11, s. 1491-1501
  • Journal article (peer-reviewed)abstract
    • Epigenetic variation may contribute to the development of complex metabolic diseases such as type 2 diabetes (T2D). Hepatic insulin resistance is a hallmark of T2D. However, it remains unknown if epigenetic alterations take place in the liver from diabetic subjects. Therefore, we investigated the genome-wide DNA methylation pattern in the liver from subjects with T2D and non-diabetic controls and related epigenetic alterations to gene expression and circulating folate levels.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Perfilyev, Alexander (1)
Ling, Charlotte (1)
Pihlajamäki, Jussi (1)
de Mello, Vanessa D. (1)
Nilsson, Emma A (1)
Matte, Ashok (1)
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Käkelä, Pirjo (1)
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University
Lund University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
Year
2015 (1)

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