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Common Breast Cance...
Common Breast Cancer Susceptibility Loci Are Associated with Triple-Negative Breast Cancer
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Stevens, Kristen N. (author)
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Vachon, Celine M. (author)
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Lee, Adam M. (author)
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show more...
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- Slager, Susan (author)
- Karolinska Institutet
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Lesnick, Timothy (author)
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Olswold, Curtis (author)
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Fasching, Peter A. (author)
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Miron, Penelope (author)
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Eccles, Diana (author)
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Carpenter, Jane E. (author)
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Godwin, Andrew K. (author)
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Ambrosone, Christine (author)
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Winqvist, Robert (author)
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Brauch, Hiltrud (author)
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Schmidt, Marjanka K. (author)
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Cox, Angela (author)
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Cross, Simon S. (author)
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Sawyer, Elinor (author)
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Hartmann, Arndt (author)
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Beckmann, Matthias W. (author)
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Schulz-Wendtland, Ruediger (author)
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Ekici, Arif B. (author)
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Tapper, William J. (author)
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Gerty, Susan M. (author)
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Durcan, Lorraine (author)
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Graham, Nikki (author)
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Hein, Rebecca (author)
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Nickels, Stephan (author)
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Flesch-Janys, Dieter (author)
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Heinz, Judith (author)
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Sinn, Hans-Peter (author)
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Konstantopoulou, Irene (author)
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Fostira, Florentia (author)
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Pectasides, Dimitrios (author)
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Dimopoulos, Athanasios M. (author)
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Fountzilas, George (author)
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Clarke, Christine L. (author)
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Balleine, Rosemary (author)
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Olson, Janet E. (author)
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Fredericksen, Zachary (author)
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Diasio, Robert B. (author)
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Pathak, Harsh (author)
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Ross, Eric (author)
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Weaver, JoEllen (author)
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Ruediger, Thomas (author)
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- Försti, Asta (author)
- Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Family Medicine and Clinical Epidemiology,Lund University Research Groups
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Duennebier, Thomas (author)
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Ademuyiwa, Foluso (author)
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Kulkarni, Swati (author)
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Pylkaes, Katri (author)
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Jukkola-Vuorinen, Arja (author)
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Ko, Yon-Dschun (author)
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Van Limbergen, Erik (author)
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Janssen, Hilde (author)
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Peto, Julian (author)
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Fletcher, Olivia (author)
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Giles, Graham G. (author)
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Baglietto, Laura (author)
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Verhoef, Senno (author)
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Tomlinson, Ian (author)
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Kosma, Veli-Matti (author)
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Beesley, Jonathan (author)
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Greco, Dario (author)
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Blomqvist, Carl (author)
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Irwanto, Astrid (author)
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Liu, Jianjun (author)
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Blows, Fiona M. (author)
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Dawson, Sarah-Jane (author)
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Margolin, Sara (author)
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Mannermaa, Arto (author)
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Martin, Nicholas G. (author)
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Montgomery, Grant W. (author)
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Lambrechts, Diether (author)
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Silva, Isabel dos Santos (author)
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Severi, Gianluca (author)
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Hamann, Ute (author)
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Pharoah, Paul (author)
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Easton, Douglas F. (author)
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Chang-Claude, Jenny (author)
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Yannoukakos, Drakoulis (author)
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Nevanlinna, Heli (author)
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Wang, Xianshu (author)
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Couch, Fergus J. (author)
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(creator_code:org_t)
- 2011
- 2011
- English.
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In: Cancer Research. - 1538-7445. ; 71:19, s. 6240-6249
- Related links:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Triple-negative breast cancers are an aggressive subtype of breast cancer with poor survival, but there remains little known about the etiologic factors that promote its initiation and development. Commonly inherited breast cancer risk factors identified through genome-wide association studies display heterogeneity of effect among breast cancer subtypes as defined by the status of estrogen and progesterone receptors. In the Triple Negative Breast Cancer Consortium (TNBCC), 22 common breast cancer susceptibility variants were investigated in 2,980 Caucasian women with triple-negative breast cancer and 4,978 healthy controls. We identified six single-nucleotide polymorphisms, including rs2046210 (ESR1), rs12662670 (ESR1), rs3803662 (TOX3), rs999737 (RAD51L1), rs8170 (19p13.1), and rs8100241 (19p13.1), significantly associated with the risk of triple-negative breast cancer. Together, our results provide convincing evidence of genetic susceptibility for triple-negative breast cancer. Cancer Res; 71(19); 6240-9. (C)2011 AACR.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Publication and Content Type
- art (subject category)
- ref (subject category)
Find in a library
To the university's database
- By the author/editor
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Stevens, Kristen ...
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Vachon, Celine M ...
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Lee, Adam M.
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Slager, Susan
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Lesnick, Timothy
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Olswold, Curtis
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show more...
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Fasching, Peter ...
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Miron, Penelope
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Eccles, Diana
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Carpenter, Jane ...
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Godwin, Andrew K ...
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Ambrosone, Chris ...
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Winqvist, Robert
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Brauch, Hiltrud
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Schmidt, Marjank ...
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Cox, Angela
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Cross, Simon S.
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Sawyer, Elinor
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Hartmann, Arndt
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Beckmann, Matthi ...
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Schulz-Wendtland ...
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Ekici, Arif B.
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Tapper, William ...
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Gerty, Susan M.
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Durcan, Lorraine
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Graham, Nikki
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Hein, Rebecca
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Nickels, Stephan
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Flesch-Janys, Di ...
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Heinz, Judith
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Sinn, Hans-Peter
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Konstantopoulou, ...
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Fostira, Florent ...
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Pectasides, Dimi ...
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Dimopoulos, Atha ...
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Fountzilas, Geor ...
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Clarke, Christin ...
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Balleine, Rosema ...
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Olson, Janet E.
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Fredericksen, Za ...
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Diasio, Robert B ...
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Pathak, Harsh
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Ross, Eric
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Weaver, JoEllen
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Ruediger, Thomas
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Försti, Asta
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Duennebier, Thom ...
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Ademuyiwa, Folus ...
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Kulkarni, Swati
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Pylkaes, Katri
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Jukkola-Vuorinen ...
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Ko, Yon-Dschun
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Van Limbergen, E ...
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Janssen, Hilde
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Peto, Julian
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Fletcher, Olivia
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Giles, Graham G.
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Baglietto, Laura
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Verhoef, Senno
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Tomlinson, Ian
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Kosma, Veli-Matt ...
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Beesley, Jonatha ...
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Greco, Dario
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Blomqvist, Carl
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Irwanto, Astrid
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Liu, Jianjun
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Blows, Fiona M.
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Dawson, Sarah-Ja ...
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Margolin, Sara
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Mannermaa, Arto
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Martin, Nicholas ...
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Montgomery, Gran ...
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Lambrechts, Diet ...
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Silva, Isabel do ...
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Severi, Gianluca
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Hamann, Ute
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Pharoah, Paul
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Easton, Douglas ...
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Chang-Claude, Je ...
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Yannoukakos, Dra ...
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Nevanlinna, Heli
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Wang, Xianshu
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Couch, Fergus J.
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
- Articles in the publication
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Cancer Research
- By the university
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Lund University
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Karolinska Institutet