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Can selective serot...
Can selective serotonin inhibitor drugs in elderly patients in nursing homes be reduced?
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- Lindström, Kjell, 1946- (författare)
- Unit of Research and Development in Primary Care, Jönköping, Sweden
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- Ekedahl, Anders (författare)
- Högskolan i Kalmar,Naturvetenskapliga institutionen,Department of Research and Development, National Corporation of Swedish Pharmacies
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- Carlsten, Anders (författare)
- Department of Research and Development, National Corporation of Swedish Pharmacies
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- Mårtensson, Jan (författare)
- Jönköping University,HHJ, Avdelningen för omvårdnad,HHJMAJA,Unit of Research and Development in Primary Care, Jönköping, Sweden and Department of Nursing Science, School of Health Sciences, Jönköping, Sweden
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- Mölstad, Sigvard, 1949- (författare)
- Linköpings universitet,Allmänmedicin,Hälsouniversitetet
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(creator_code:org_t)
- 2009-07-12
- 2007
- Engelska.
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Ingår i: Scandinavian Journal of Primary Health Care. - London : Informa Healthcare. - 0281-3432 .- 1502-7724. ; 25:1, s. 3-8
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Abstract
Ämnesord
Stäng
- OBJECTIVE: To investigate whether treatment with selective serotonin reuptake inhibitors (SSRIs) could be withdrawn for elderly residents who had been on treatment for at least one year and to evaluate a method for systematic drug review. DESIGN: Open, prospective, interventional study. SETTING: Four counties in Sweden. SUBJECTS: Elderly residents at 19 nursing homes, with ongoing treatment with SSRIs for more than one year. MAIN OUTCOME MEASURES: Clinical evaluation, registration of drugs used and rating with Montgomery-Asberg Depression Rating Scale (MADRS). A semi-structured telephone interview with 15 participating physicians and 19 nurses. RESULTS: About one-third of all 822 residents in the nursing homes had ongoing antidepressant treatment, predominantly with SSRIs; 75% of them had been treated with SSRIs for at least one year and 119 (60%) of these were considered eligible for the study. The intervention was judged successful in 52% of these residents of whom 88% had a MADRS rating of less than 20 points. The GPs and the nurses experienced the method as practicable. CONCLUSIONS: Withdrawal of SSRI treatment was successful in the majority of cases. The MADRS may be a valuable addition to clinical evaluation when deciding whether to end or continue SSRI treatment.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Samhällsfarmaci och klinisk farmaci (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Social and Clinical Pharmacy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
- SAMHÄLLSVETENSKAP -- Annan samhällsvetenskap -- Övrig annan samhällsvetenskap (hsv//swe)
- SOCIAL SCIENCES -- Other Social Sciences -- Other Social Sciences not elsewhere specified (hsv//eng)
Nyckelord
- Family practice
- Nursing homes
- SSRI drugs
- Systematic drug review
- Withdrawal
- Community pharmacy services
- Samhällsfarmaci
- Natural Science
- Naturvetenskap
- Pharmacology
- Farmakologi
- Biological research on drug dependence
- Older people and ageing
- MEDICINE
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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