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Methodological issu...
Methodological issues in the diagnostic work-up of food allergy : a real challenge.
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- Gellerstedt, Martin, 1966- (författare)
- Högskolan Väst,Avd för datavetenskap och informatik,Department of Informatics, University West, Trollhättan, Sweden
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- Bengtsson, U (författare)
- The Asthma and Allergy Research Group, Department of Respiratory Medicine and Allergy, Sahlgrenska University Hospital, Gothenburg, Sweden
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- Niggemann, B (författare)
- Department of Pneumology and Immunology, University Children’s Hospital Charité, Berlin, Germany
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(creator_code:org_t)
- Barcelona : J.R. Prous, S.A, 2007
- 2007
- Engelska.
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Ingår i: Journal of investigational allergology & clinical immunology. - Barcelona : J.R. Prous, S.A. - 1018-9068 .- 1698-0808. ; 17:6, s. 350-356
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Abstract
Ämnesord
Stäng
- The standard of reporting in diagnostic studies has generally been low. Fortunately, this issue has begun to be addressed in recent years through the discussion of important methodological issues in educational series, textbooks, and checklists. Double-blind, placebo-controlled, oral food challenges (DBPCFC) are considered to be the gold standard for diagnosis of food allergy. However, there is no consensus regarding how to interpret the outcome and how to define positive and negative provocations in DBPCFC. Furthermore, since most theories on the diagnosis of food allergy rely on the assumption that the DBPCFC has a high accuracy, this accuracy must be formally statistically evaluated. In this review, we discuss essential methodological issues for diagnostic accuracy studies in general and for oral food challenges in particular and discuss the importance of methodological issues as a guide for forthcoming studies of diagnostic procedures.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Immunologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Immunology in the medical area (hsv//eng)
Nyckelord
- Diagnostic accuracy
- Food allergy
- Food challenge
- Methodological issues
- Allergology
- Allergologi
- Informatics
- Informatik
- Vårdvetenskap
- Nursing science
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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