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New Transmission Co...
Abstract
Ämnesord
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- The Bloch-Torrey Partial Differential Equation (PDE) can be used to model the diffusion Magnetic Resonance Imaging (dMRI) signal in biological tissue. In this paper, we derive an Anisotropic Diffusion Transmission Condition (ADTC) for the Bloch-Torrey PDE that accounts for anisotropic diffusion inside thin layers. Such diffusion occurs, for example, in the myelin sheath surrounding the axons of neurons. This ADTC can be interpreted as an asymptotic model of order two with respect to the layer thickness and accounts for water diffusion in the normal direction that is low compared to the tangential direction. We prove the uniform stability of the asymptotic model with respect to the layer thickness and a mass conservation property. We also prove the theoretical quadratic accuracy of the ADTC. Finally, numerical tests validate these results and show that our model gives a better approximation of the dMRI signal than a simple transmission condition that assumes isotropic diffusion in the layers.
Nyckelord
- Asymptotic expansion
- Bloch-Torrey equation
- anisotropic diffusion transmission condition
- diffusion magnetic resonance imaging
- Tillämpad matematik och beräkningsmatematik
- Applied and Computational Mathematics
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- ref (ämneskategori)
- art (ämneskategori)
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