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Does Botulinum toxi...
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Engström, PährKarolinska Institutet
(författare)
Does Botulinum toxin A improve the walking pattern in children with idiopathic toe-walking?
- Artikel/kapitelEngelska2010
Förlag, utgivningsår, omfång ...
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2010-08-01
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SAGE Publications,2010
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:kth-74930
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https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-74930URI
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https://doi.org/10.1007/s11832-010-0263-9DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:221804891URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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QC 20120217
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Background: Numerous recommendations have been made for treating idiopathic toe-walking (ITW), but the treatment results have been questioned. The purpose of this study was to investigate whether botulinum toxin A (BTX) improves the walking pattern in ITW as examined with 3-D gait analysis. Participants and methods: A consecutive series of 15 children (aged 5-13 years) were enrolled in the study. The children underwent a 3-D gait analysis prior to treatment with a total of 6 units/kg bodyweight Botox® in the calf muscles and an exercise program. The gait analysis was repeated 3 weeks and 3, 6, and 12 months after treatment. A classification of toe-walking severity was made before treatment and after 12 months. The parents rated the perceived amount of toe-walking prior to treatment and 6 and 12 months after treatment. Results: Eleven children completed the 12-month follow-up. The gait analysis results displayed a significant improvement, indicating decreased plantarflexion angle at initial contact and during swing phase and increased dorsiflexion angle during midstance at all post-treatment testing instances. According to the parents' perception of toe-walking, 3/11 children followed for 12 months had ceased toe-walking completely, 4/11 decreased toe-walking, and 4/11 continued toe-walking. After 6-12 months, the toe-walking severity classification improved in 9 of the 14 children for whom data could be assessed. Conclusions: A single injection of BTX in combination with an exercise program can improve the walking pattern in children with ITW seen at gait analysis, but the obvious goal of ceasing toe-walking is only occasionally reached.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Gutierrez-Farewik, Elena,1973-Karolinska Institutet,KTH,Biomekanik,Strukturmekanik,Anders Eriksson(Swepub:kth)u1tekbf6
(författare)
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Bartonek, ÅsaKarolinska Institutet
(författare)
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Tedroff, KristinaKarolinska Institutet
(författare)
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Orefelt, ChristinaKarolinska Institutet, Dept. of Women's and Children's Health
(författare)
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Haglund-Åkerlind, YvonneKarolinska Institutet, Dept. of Women's and Children's Health
(författare)
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Karolinska InstitutetBiomekanik
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Journal of Children's Orthopaedics: SAGE Publications4:4, s. 301-3081863-25211863-2548
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