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Sciatic nerve blood...
Sciatic nerve blood flow measured by laser Doppler flowmetry and [14C]iodoantipyrine.
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Rundquist, I (författare)
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Smith, Q R (författare)
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Michel, M E (författare)
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visa fler...
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- Ask, Per (författare)
- Linköpings universitet,Fysiologisk mätteknik,Tekniska högskolan
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- Öberg, Åke (författare)
- Linköpings universitet,Institutionen för medicinsk teknik,Tekniska högskolan
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Rapoport, S I (författare)
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visa färre...
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(creator_code:org_t)
- 1985
- 1985
- Engelska.
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Ingår i: American Journal of Physiology. - 0002-9513 .- 2163-5773. ; 248:3 Pt 2, s. H311-317
- Relaterad länk:
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https://urn.kb.se/re...
Abstract
Ämnesord
Stäng
- Blood flow was examined in sciatic nerves of pentobarbital-anesthetized rats by means of laser Doppler flowmetry (LDF) and intravenous [14C]iodoantipyrine infusion. Continuous LDF signals demonstrated slow oscillations and acute, pressure-related changes in flow. The steady-state LDF signal was related linearly to nerve blood flow, as measured with [14C]iodoantipyrine, in intact nerves and nerves stripped of the epineurium. In 14 intact nerves, nerve blood flow averaged 0.27 +/- 0.03 (SE) ml X min-1 X g-1, whereas it averaged 0.13 +/- 0.01 in 5 stripped nerves. Autoradiographs of [3H]-nicotine-infused nerves and intra-arterial injection of 57Co-labeled microspheres demonstrated that flow was not uniform throughout the nerve cross section. The results indicate that LDF can be used to examine nerve blood flow in vivo, demonstrate a linear relation between the LDF signal and flow, and establish absolute values for blood flow in intact and stripped nerves of the anesthetized rat.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Maskinteknik -- Strömningsmekanik och akustik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Mechanical Engineering -- Fluid Mechanics and Acoustics (hsv//eng)
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- ref (ämneskategori)
- art (ämneskategori)
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