Sökning: onr:"swepub:oai:DiVA.org:liu-127261" >
Effects of salience...
-
Hamilton, Paul J.Linköpings universitet,Avdelningen för neuro- och inflammationsvetenskap,Medicinska fakulteten,Centrum för social och affektiv neurovetenskap (CSAN)
(författare)
Effects of salience-network-node neurofeedback training on affective biases in major depressive disorder
- Artikel/kapitelEngelska2016
Förlag, utgivningsår, omfång ...
-
Elsevier,2016
-
printrdacarrier
Nummerbeteckningar
-
LIBRIS-ID:oai:DiVA.org:liu-127261
-
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-127261URI
-
https://doi.org/10.1016/j.pscychresns.2016.01.016DOI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
Funding Agencies|National Institutes of Health [P41 EB15891, F32 MH079651, R01 MH59259]
-
Neural models of major depressive disorder (MDD) posit that over-response of components of the brains salience network (SN) to negative stimuli plays a crucial role in the pathophysiology of MDD. In the present proof-of-concept study, we tested this formulation directly by examining the affective consequences of training depressed persons to down-regulate response of SN nodes to negative material. Ten participants in the real neurofeedback group saw, and attempted to learn to down-regulate, activity from an empirically identified node of the SN. Ten other participants engaged in an equivalent procedure with the exception that they saw SN-node neurofeedback indices from participants in the real neurofeedback group. Before and after scanning, all participants completed tasks assessing emotional responses to negative scenes and to negative and positive self-descriptive adjectives. Compared to participants in the sham-neurofeedback group, from pre- to post-training, participants in the realneurofeedback group showed a greater decrease in SN-node response to negative stimuli, a greater decrease in self-reported emotional response to negative scenes, and a greater decrease in self-reported emotional response to negative self-descriptive adjectives. Our findings provide support for a neural formulation in which the SN plays a primary role in contributing to negative cognitive biases in MDD. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Glover, Gary H.Stanford University, CA, USA
(författare)
-
Bagarinao, EpifanioStanford University, CA, USA
(författare)
-
Chang, CatieNational Institutes of Health, Bethesda, MD, USA
(författare)
-
Mackey, SeanStanford University, CA, USA
(författare)
-
Sacchet, Matthew D.Stanford University, CA, USA
(författare)
-
Gotlib, Ian H.Stanford University, CA, USA
(författare)
-
Linköpings universitetAvdelningen för neuro- och inflammationsvetenskap
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Psychiatry Research: Elsevier249, s. 91-960925-49271872-7506
Internetlänk
Hitta via bibliotek
Till lärosätets databas