Sökning: onr:"swepub:oai:DiVA.org:liu-154816" >
Reduced pain thresh...
-
Grundström, Hanna,1982-Linköpings universitet,Avdelningen för omvårdnad,Medicinska fakulteten,Region Östergötland, Kvinnokliniken ViN
(författare)
Reduced pain thresholds and signs of sensitization in women with persistent pelvic pain and suspected endometriosis
- Artikel/kapitelEngelska2019
Förlag, utgivningsår, omfång ...
-
2018-12-30
-
John Wiley & Sons,2019
-
electronicrdacarrier
Nummerbeteckningar
-
LIBRIS-ID:oai:DiVA.org:liu-154816
-
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-154816URI
-
https://doi.org/10.1111/aogs.13508DOI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
Funding agencies: Medical Research Council of Southeast Sweden; Region Ostergotland; Linkoping University
-
INTRODUCTION: Endometriosis is a gynecological disorder that may cause considerable pelvic pain in women of fertile age. Determining pain mechanisms is necessary in order to optimize the treatment of the disease. The objective of the study was to evaluate pain thresholds in women with persistent pelvic pain with and without confirmed endometriosis, and healthy, unaffected controls, and analyze how pain thresholds in these cohorts related to duration of pelvic pain, quality of life, and symptoms of anxiety and depression.MATERIAL AND METHODS: Pain thresholds for heat, cold and pressure were assessed with quantitative sensory testing on six locations on a reference group of 55 healthy women and on 37 women with persistent pelvic pain who had been admitted for diagnostic laparoscopy on the suspicion of endometriosis. Validated instruments were applied to assess quality of life and symptoms of anxiety and depression. Data were analyzed by means of uni- and multivariate analysis of variance and Spearman's rank-order correlation.RESULTS: The women with persistent pelvic pain had significantly lower pain thresholds compared with the reference women. In the women with pain, no differences were observed in pain thresholds between women with (n = 13) and women without (n = 24) biopsy-proven endometriosis. The duration of pelvic pain correlated significantly positively with reduced pain thresholds, ie, the longer the duration, the more sensitization. In the persistent pelvic pain group, pain thresholds for heat correlated significantly with the Short Form Health Survey 36 dimension of bodily pain, and thresholds for cold correlated with Short Form Health Survey 36 bodily pain and with symptoms of depression.CONCLUSIONS: Our results showed widespread alterations in pain thresholds in women with persistent pelvic pain that are indicative of central sensitization and a time-dependent correlation. Women with pelvic pain and suspicion of endometriosis should probably be treated more thoroughly to prevent or at least minimize the concomitant development of central sensitization.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Gerdle, Björn,1953-Linköpings universitet,Avdelningen för samhällsmedicin,Medicinska fakulteten,Region Östergötland, Smärt och rehabiliteringscentrum(Swepub:liu)bjoge88
(författare)
-
Alehagen, Siw,1953-Linköpings universitet,Avdelningen för omvårdnad,Medicinska fakulteten(Swepub:liu)siwal91
(författare)
-
Berterö, Carina,1959-Linköpings universitet,Avdelningen för omvårdnad,Medicinska fakulteten(Swepub:liu)carbe13
(författare)
-
Arendt-Nielsen, LarsCenter for Sensory‐Motor Interactions, Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark
(författare)
-
Kjölhede, Preben,1957-Linköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Region Östergötland, Kvinnokliniken US(Swepub:liu)prekj14
(författare)
-
Linköpings universitetAvdelningen för omvårdnad
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Acta Obstetricia et Gynecologica Scandinavica: John Wiley & Sons98:3, s. 327-3360001-63491600-0412
Internetlänk
Hitta via bibliotek
Till lärosätets databas