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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03839naa a2200349 4500 | |
| 001 | oai:DiVA.org:liu-173865 | |
| 003 | SwePub | |
| 008 | 210309s2021 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-1738652 URI |
| 024 | 7 | a https://doi.org/10.1038/s41598-021-82268-32 DOI |
| 040 | a (SwePub)liu | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Zhao, Mingduou Linköpings universitet,Avdelningen för sinnesorgan och kommunikation,Medicinska fakulteten4 aut0 (Swepub:liu)minzh66 |
| 245 | 1 0 | a Vibration direction sensitivity of the cochlea with bone conduction stimulation in guinea pigs |
| 264 | c 2021-02-03 | |
| 264 | 1 | b Nature Research,c 2021 |
| 338 | a electronic2 rdacarrier | |
| 500 | a Funding Agencies|Linkoping University | |
| 520 | a Sound and vibrations that cause the skull bone to vibrate can be heard as ordinary sounds and this is termed hearing by bone conduction (BC). Not all mechanisms that causes a skull vibration to result in BC hearing are known, and one such unknown is how the direction of the vibration influences BC hearing. This direction sensitivity was investigated by providing BC stimulation in five different directions at the vertex of the guinea pig skull. The hearing thresholds for BC stimulation was obtained in the frequency range of 2 to 20 kHz by measurements of compound action potential. During the stimulation by BC, the vibration of the cochlear promontory was measured with a three-dimensional laser Doppler vibrometer resulting in a set of unique three-dimensional velocity magnitude combinations for each threshold estimation. The sets of three-dimensional velocity magnitude at threshold were used to investigate nine different predictors of BC hearing based on cochlear promontory velocity magnitudes, six single direction (x, y and z directions in isolation, the normal to the stapes footplate, the oval to round window direction, and the cochlear base to apex direction), one linear combination of the three dimension velocity magnitudes, one square-rooted sum of the squared velocity magnitudes, and one sum of the weighted three dimensional velocity magnitudes based on a restricted minimum square error (MSE) estimation. The MSE gave the best predictions of the hearing threshold based on the cochlear promontory velocity magnitudes while using only a single direction gave the worst predictions of the hearing thresholds overall. According to the MSE estimation, at frequencies up to 8 kHz the vibration direction between the right and left side gave the greatest contribution to BC hearing in the guinea pig while at the highest frequencies measured, 16 and 20 kHz, the anteroposterior direction of the guinea pig head gave the greatest contribution. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Oto-rhino-laryngologi0 (SwePub)302182 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Otorhinolaryngology0 (SwePub)302182 hsv//eng |
| 700 | 1 | a Fridberger, Andersu Linköpings universitet,Avdelningen för neurobiologi,Medicinska fakulteten4 aut0 (Swepub:liu)andfr39 |
| 700 | 1 | a Stenfelt, Stefanu Linköpings universitet,Avdelningen för sinnesorgan och kommunikation,Medicinska fakulteten4 aut0 (Swepub:liu)stest78 |
| 710 | 2 | a Linköpings universitetb Avdelningen för sinnesorgan och kommunikation4 org |
| 773 | 0 | t Scientific Reportsd : Nature Researchg 11:1q 11:1x 2045-2322 |
| 856 | 4 | u https://liu.diva-portal.org/smash/get/diva2:1535953/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
| 856 | 4 | u https://www.nature.com/articles/s41598-021-82268-3.pdf |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-173865 |
| 856 | 4 8 | u https://doi.org/10.1038/s41598-021-82268-3 |
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