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Sökning: onr:"swepub:oai:DiVA.org:liu-202497" > The association of ...

  • de Lange, Dylan W.Univ Utrecht, Netherlands (författare)

The association of premorbid conditions with 6-month mortality in acutely admitted ICU patients over 80 years

  • Artikel/kapitelEngelska2024

Förlag, utgivningsår, omfång ...

  • SPRINGER,2024
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:liu-202497
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-202497URI
  • https://doi.org/10.1186/s13613-024-01246-wDOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Funding Agencies|DRC Ile de France; URC Est helped conducting VIP2 in France
  • Background Premorbid conditions influence the outcome of acutely ill adult patients aged 80 years and over who are admitted to the ICU. The aim of this study was to determine the influence of such premorbid conditions on 6 month survival. Methods Prospective cohort study in 242 ICUs from 22 countries including patients 80 years or above, admitted over a 6 months period to an ICU between May 2018 and May 2019. Only emergency (acute) ICU admissions in adult patients >= 80 years of age were eligible. Patients who were admitted after planned/elective surgery were excluded. We measured the Clinical Frailty Scale (CFS), the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), disability with the Katz activities of daily living (ADL) score, comorbidities and a Polypharmacy Score (CPS). Results Overall, the VIP2 study included 3920 patients. During ICU stay 1191 patients died (30.9%), and another 436 patients (11.1%) died after ICU discharge but within the first 30 days of admission, and an additional 895 patients died hereafter but within the first 6 months after admission (22.8%). The 6 months mortality was 64%. The median CFS was 4 (IQR 3-6). Frailty (CFS >= 5) was present in 26.6%. Cognitive decline (IQCODE above 3.5) was found in 30.2%. The median IQCODE was 3.19. A Katz ADL of 4 or less was present in 27.7%. Patients who surviving > 6 months were slightly younger (median age survivors 84 with IQR 81-86) than patients dying within the first 6 months (median age 84, IQR 82-87, p = 0.013), were less frequently frail (CFS > 5 in 19% versus 34%, p < 0.01) and were less dependent based on their Katz activities of daily living measurement (median Katz score 6, IQR 5-6 versus 6 points, IQR 3-6, p < 0.01). Conclusions We found that Clinical Frailty Scale, age, and SOFA at admission were independent prognostic factors for 6 month mortality after ICU admission in patients age 80 and above. Adding other geriatric syndromes and scores did not improve the model. This information can be used in shared-decision making. ClinicalTrials.gov: NCT03370692. Conclusions We found that Clinical Frailty Scale, age, and SOFA at admission were independent prognostic factors for 6 month mortality after ICU admission in patients age 80 and above. Adding other geriatric syndromes and scores did not improve the model. This information can be used in shared-decision making.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Soliman, Ivo W.Univ Utrecht, Netherlands (författare)
  • Leaver, SusannahSt George Hosp, England (författare)
  • Boumendil, ArianeHop St Antoine, France (författare)
  • Haas, Lenneke E. M.Diakonessen Hosp, Netherlands (författare)
  • Watson, XimenaSt George Hosp, England (författare)
  • Boulanger, CarolRoyal Devon & Exeter NHS Fdn Trust, England (författare)
  • Szczeklik, WojciechJagiellonian Univ Med Coll, Poland (författare)
  • Artigas, AntonioAutonomous Univ Barcelona, Spain; Sagrado Corazon Gen Cataluna Univ Hosp, Spain (författare)
  • Morandi, AlessandroHosp Ancelle Cremona, Italy; Geriatr Res Grp, Italy (författare)
  • Andersen, FinnAlesund Hosp, Norway; NTNU, Norway (författare)
  • Jung, ChristianUniv Hosp Dusseldorf, Germany (författare)
  • Moreno, RuiCtr Hosp Univ Lisboa Cent, Portugal; Univ Beira Interior, Portugal (författare)
  • Walther, Sten M.,1954-Region Östergötland, Thorax-kärlkliniken i Östergötland(Swepub:liu)stewa50 (författare)
  • Oeyen, SandraGhent Univ Hosp, Belgium (författare)
  • Schefold, Joerg C.Univ Bern, Switzerland (författare)
  • Cecconi, MaurizioIRCCS, Italy; Humanitas Univ, Italy (författare)
  • Marsh, BrianMater Misericordiae Univ Hosp, Ireland (författare)
  • Joannidis, MichaelMed Univ Innsbruck, Austria (författare)
  • Nalapko, YuriyICU, Ukraine (författare)
  • Elhadi, MuhammedICU, Alkhums Hosp, Libya (författare)
  • Fjolner, JesperViborg Reg Hosp, Denmark (författare)
  • Guidet, BertrandHop St Antoine, France (författare)
  • Flaatten, HansUniv Bergen, Norway (författare)
  • Univ Utrecht, NetherlandsSt George Hosp, England (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Annals of Intensive Care: SPRINGER14:12110-5820

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