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Elevated number of ...
Elevated number of cells secreting transforming growth factor β in Guillain-Barré syndrome
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- Dahle, Charlotte (författare)
- Linköpings universitet,Neurologi,Klinisk immunologi,Hälsouniversitetet
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- Kvarnström, Maria (författare)
- Linköpings universitet,Klinisk immunologi,Hälsouniversitetet
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- Ekerfelt, Christina (författare)
- Linköpings universitet,Klinisk immunologi,Hälsouniversitetet
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- Samuelsson, Margareta (författare)
- Neurology Unit, Örebro University Hospital, Sweden
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- Ernerudh, Jan (författare)
- Linköpings universitet,Neurologi,Klinisk immunologi,Hälsouniversitetet
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(creator_code:org_t)
- Wiley, 2003
- 2003
- Engelska.
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Ingår i: Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). - : Wiley. - 0903-4641 .- 1600-0463. ; 111:12, s. 1095-1104
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- We used ELISPOT and cell ELISA to study secretion of IL-4, IFN-γ, TGF-β, IL-6, and TNF-α by circulating mononuclear cells during the course of Guillain-Barré syndrome (GBS). Compared to healthy controls, patients with GBS had higher numbers of TGF-β-secreting cells and the number of individuals with myelin-peptide-induced IL-4 and TGF-β secretion was higher in the GBS group. No significant differences were seen concerning the predominantly pro-inflammatory cytokines IFN-γ, IL-6 or TNF-α. Our findings indicate a down-regulatory role for TGF-β and IL-4 in GBS.
Nyckelord
- Cytokines
- ELISPOT
- Guillain-Barré
- IL-4
- Syndrome
- TGF-ß
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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