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Impact of tumour si...
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Jancke, GeorgLinköpings universitet,Hälsouniversitetet,Onkologi
(författare)
Impact of tumour size on recurrence and progression in Ta/T1 carcinoma of the urinary bladder
- Artikel/kapitelEngelska2011
Förlag, utgivningsår, omfång ...
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2011-06-16
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Informa Healthcare,2011
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:liu-72650
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-72650URI
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https://doi.org/10.3109/00365599.2011.590995DOI
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Språk:engelska
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Sammanfattning på:engelska
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Klassifikation
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Objective. This study aimed to evaluate the impact of tumour size on recurrence and progression in a population-based series of non-muscle-invasive bladder cancers. Material and methods. Clinical and pathological characteristics of patients with primary Ta/bladder cancer were registered. The patients tumours were categorized by size into five size groups (1-10, 11-20, 21-30, 31-40 and andgt;40 mm) or three size groups (1-15, 16-30 and andgt;30 mm). Results. The analysis included 768 evaluable patients with a mean follow-up of 60 months. Recurrence was observed in 478 patients (62%) and progression in 71 (9%). Tumour size was associated with recurrence for tumours sized 21-30, 31-40 and andgt;40 mm (p = 0.03, p andlt; 0.001, p andlt; 0.001, respectively) in the five size group and for tumours sized 16-30 and andgt;30 mm (p = 0.003 and p andlt; 0.001) in the three size group. Other factors affecting recurrence were T1 tumour category, multiplicity and surgery performed by residents (p andlt; 0.001, p andlt; 0.001, p = 0.002, respectively). Considering progression, there was no significant association with tumour size, and T1 category and local recurrence were the only significant risk factors (both p andlt; 0.001). Conclusion. Tumour size andlt;= 15 mm is associated with a lower risk of recurrence but not progression. Dividing tumour size into three size groups gives additional information compared with two size groups with cut-off at 30 mm.
Ämnesord och genrebeteckningar
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progression
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recurrence
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tumour size
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urinary bladder cancer
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MEDICINE
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MEDICIN
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Rosell, JohanÖstergötlands Läns Landsting,Linköpings universitet,Onkologi,Hälsouniversitetet,Onkologiska kliniken US(Swepub:liu)johro19
(författare)
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Jahnson, StaffanÖstergötlands Läns Landsting,Linköpings universitet,Kirurgi,Hälsouniversitetet,Urologiska kliniken i Östergötland(Swepub:liu)staja74
(författare)
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Linköpings universitetHälsouniversitetet
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Scandinavian Journal of Urology and Nephrology: Informa Healthcare45:6, s. 388-3920036-55991651-2065
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