Imaging, virtual planning, design and production of patient specific implants and clinical validation in cranio-maxillo-facial surgery

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Dérand, Per (författare)

Imaging, virtual planning, design and production of patient specific implants and clinical validation in cranio-maxillo-facial surgery

Artikel/kapitelEngelska2012

Förlag, utgivningsår, omfång ...

2012-09-01
SAGE Publications,2012
printrdacarrier

Nummerbeteckningar

LIBRIS-ID:oai:DiVA.org:miun-18067
https://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-18067URI
https://doi.org/10.1055/s-0032-1313357DOI

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Språk:engelska
Sammanfattning på:engelska

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Ämneskategori:art swepub-publicationtype

Anmärkningar

The purpose of this article was to describe the workflow from imaging, via virtual design, to manufacturing of patient-specific titanium reconstruction plates, cutting guide and mesh, and its utility in connection with surgical treatment of acquired bone defects in the mandible using additive manufacturing by electron beam melting (EBM). Based on computed tomography scans, polygon skulls were created. Following that virtual treatment plans entailing free microvascular transfer of fibula flaps using patient-specific reconstruction plates, mesh, and cutting guides were designed. The design was based on the specification of a Compact UniLOCK 2.4 Large (Synthes®, Switzerland). The obtained polygon plates were bent virtually round the reconstructed mandibles. Next, the resections of the mandibles were planned virtually. A cutting guide was outlined to facilitate resection, as well as plates and titanium mesh for insertion of bone or bone substitutes. Polygon plates and meshes were converted to stereolithography format and used in the software Magics for preparation of input files for the successive step, additive manufacturing. EBM was used to manufacture the customized implants in a biocompatible titanium grade, Ti6Al4V ELI. The implants and the cutting guide were cleaned and sterilized, then transferred to the operating theater, and applied during surgery. Commercially available software programs are sufficient in order to virtually plan for production of patient-specific implants. Furthermore, EBM-produced implants are fully usable under clinical conditions in reconstruction of acquired defects in the mandible. A good compliance between the treatment plan and the fit was demonstrated during operation. Within the constraints of this article, the authors describe a workflow for production of patient-specific implants, using EBM manufacturing. Titanium cutting guides, reconstruction plates for fixation of microvascular transfer of osteomyocutaneous bone grafts, and mesh to replace resected bone that can function as a carrier for bone or bone substitutes were designed and tested during reconstructive maxillofacial surgery. A clinically fit, well within the requirements for what is needed and obtained using traditional free hand bending of commercially available devices, or even higher precision, was demonstrated in ablative surgery in four patients.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kirurgi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Surgery hsv//eng

Biuppslag (personer, institutioner, konferenser, titlar ...)

Rännar, Lars-ErikMittuniversitetet,Institutionen för teknik och hållbar utveckling (-2013)(Swepub:miun)larran (författare)
Hirsch, Jan-M (författare)
MittuniversitetetInstitutionen för teknik och hållbar utveckling (-2013) (creator_code:org_t)

Sammanhörande titlar

Ingår i:Cranial maxillofacial Trauma and Reconstruction: SAGE Publications5:3, s. 137-1441943-38751943-3883

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Cranial maxillofacial Trauma and Reconstruction (Sök värdpublikationen i LIBRIS)

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Av författaren/redakt...: Dérand, Per; Rännar, Lars-Eri ...; Hirsch, Jan-M

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Kirurgi

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