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Sökning: onr:"swepub:oai:DiVA.org:oru-12130" > Changes in plasma C...

  • Thøgersen, Anna M. (författare)

Changes in plasma C-reactive protein and hemostatic factors prior to and after a first myocardial infarction with a median follow-up time of 8 years

  • Artikel/kapitelEngelska2009

Förlag, utgivningsår, omfång ...

  • 2009
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:oru-12130
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-12130URI
  • https://doi.org/10.1097/MBC.0b013e32832a5fd1DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-23470URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • The objective of this study was to determine whether a first myocardial infarction leads to increased plasma levels of hemostatic factors and high sensitive C-reactive protein (hs-CRP) and whether the association between theses biomarkers and myocardial infarction was greater at follow-up compared with baseline. Of more than 36,000 persons screened in northern Sweden, 78 developed a first myocardial infarction (on average 18 months after sampling) in a population-based, prospective, nested patient-referent study. Fifty of these had participated in a follow-up health survey (on average 8 and a half years between surveys) and were sex-matched and age-matched with 56 referents. The mean increases in hs-CRP, tissue plasminogen activator (tPA) mass, plasminogen activator inhibitor-1 mass, and tPA/plasminogen activator inhibitor-1 complex concentration and von Willebrand factor among patients and referents were comparable during follow-up. Conditional logistic regression indicated that hs-CRP was not significantly associated with first myocardial infarction in a univariate analysis, whereas high plasma levels of tPA and creatinine were significantly associated with outcome at baseline and follow-up. tPA/plasminogen activator inhibitor-1 complex was not superior to tPA as a risk marker in this study. A first myocardial infarction did not in this study induce significantly different changes in plasma levels of hs-CRP and hemostatic factors among patients compared with referents during follow-up.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Nilsson, Torbjörn K.Örebro universitet,Hälsoakademin(Swepub:oru)tnnn (författare)
  • Weinehall, LarsUmeå universitet,Epidemiologi och folkhälsovetenskap(Swepub:umu)lawe0001 (författare)
  • Boman, KurtUmeå universitet,Medicin(Swepub:umu)kubo0001 (författare)
  • Eliasson, MatsUmeå universitet,Medicin(Swepub:umu)mael0021 (författare)
  • Hallmans, GöranUmeå universitet,Näringsforskning(Swepub:umu)goha0001 (författare)
  • Jansson, Jan-HåkanUmeå universitet,Medicin(Swepub:umu)jaja0006 (författare)
  • Örebro universitetHälsoakademin (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Blood Coagulation and Fibrinolysis20:5, s. 340-3460957-52351473-5733

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