Perfluorinated chemicals in blood of residents in Catalonia (Spain) in relation to age and gender: a pilot study

Ericson Jogsten, IngridÖrebro universitet,Institutionen för naturvetenskap,MTM (författare)

Perfluorinated chemicals in blood of residents in Catalonia (Spain) in relation to age and gender : a pilot study

Fluorinated organic compounds (FOCs) are a group of chemicals widely used as surfactants, lubricants, polymers, and fire-fighting foams. Recent studies have shown the ubiquitous distribution of FOCs in the environment, wildlife, and humans. We here report the results of a pilot study conducted to provide preliminary data on the levels of 13 FOCs in the blood of 48 residents in Catalonia, Spain, in relation to gender and age (25+/-5 and 55+/-5 years). The highest mean concentration was obtained for perfluorooctane sulfonate (PFOS, 7.64 ng/ml), followed by perfluorohexane sulfonate (PFHxS, 3.56 ng/ml) and perfluorooctanoic acid (PFOA, 1.80 ng/ml). Four other FOCs showed mean levels between 0.30 and 0.44 ng/ml, whereas those of the remaining 6 compounds were below the detection limit. Regarding gender, the blood levels of PFHxS and PFOA were significantly higher (p<0.05) in men than in women, while differences according to age were only noted for PFHxS (p<0.05) and perfluorooctane sulfonamide (PFOSA) (p<0.001), for which the levels were higher in the younger (25+/-5 years) group of subjects. A significant correlation between PFOS levels and those of the remaining detected FOCs (except PFDA) was found. In general terms, the current FOC concentrations were lower than those found in recent studies concerning levels of these chemicals in human blood and serum of subjects from different countries.

Gómez, Mercedes (författare)
Nadal, Martí (författare)
van Bavel, BertÖrebro universitet,Institutionen för naturvetenskap,MTM(Swepub:oru)bvl (författare)
Lindström, GunillaÖrebro universitet,Institutionen för naturvetenskap,MTM(Swepub:oru)glm (författare)
Domingo, José L. (författare)
Örebro universitetInstitutionen för naturvetenskap (creator_code:org_t)

Ingår i:Environment International: Elsevier BV33:5, s. 616-6230160-41201873-6750

Av författaren/redakt...: Ericson Jogsten, ...; Gómez, Mercedes; Nadal, Martí; van Bavel, Bert; Lindström, Gunil ...; Domingo, José L.

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