Sökning: onr:"swepub:oai:DiVA.org:oru-54591" > Mediators of the as...
Fältnamn | Indikatorer | Metadata |
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000 | 04128naa a2200469 4500 | |
001 | oai:DiVA.org:oru-54591 | |
003 | SwePub | |
008 | 170112s2014 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:129601934 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-545912 URI |
024 | 7 | a https://doi.org/10.1016/j.annepidem.2014.05.0102 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1296019342 URI |
040 | a (SwePub)orud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a McCoy, Brittany M.u Department of Psychological and Brain Sciences, Indiana University Bloomington, Bloomington, USA4 aut |
245 | 1 0 | a Mediators of the association between parental severe mental illness and offspring neurodevelopmental problems |
264 | 1 | a New York, USA :b Elsevier,c 2014 |
338 | a print2 rdacarrier | |
500 | a Funding Agencies:National Institute of Child Health and Human Development National Institute of Mental Health Swedish council for working life and social research Swedish Society of Medicine | |
520 | a Purpose: Parental severe mental illness (SMI) is associated with an increased risk of offspring autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). We conducted a study to examine the extent to which risk of preterm birth, low birth weight, and small for gestational age mediated this association.Methods: We obtained data on offspring born 1992-2001 in Sweden (n = 870,017) through the linkage of multiple population-based registers. We used logistic and Cox regression to assess the associations between parental SMI, adverse pregnancy outcomes, and offspring ASD and ADHD, as well as tested whether adverse pregnancy outcomes served as mediators.Results: After controlling for measured covariates, maternal and paternal SMI were associated with an increased risk for preterm birth, low birth weight, and gestational age, and for offspring ASD and ADHD. These pregnancy outcomes were also associated with an increased risk of ASD and ADHD. We found that pregnancy outcomes did not mediate the association between parental SMI and offspring ASD and ADHD, as there was no substantial change in magnitude of the risk estimates after controlling for pregnancy outcomes.Conclusions: Parental SMI and adverse pregnancy outcomes appear to be independent risk factors for offspring ASD and ADHD. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng |
653 | a Attention deficit hyperactivity disorder | |
653 | a autism spectrum disorder | |
653 | a infant | |
653 | a small for gestational age | |
653 | a birth weight | |
653 | a gestational age | |
700 | 1 | a Rickert, Martin E.u Department of Psychological and Brain Sciences, Indiana University Bloomington, Bloomington, USA4 aut |
700 | 1 | a Class, Quetzal A.u Department of Psychological and Brain Sciences, Indiana University Bloomington, Bloomington, USA4 aut |
700 | 1 | a Larsson, Henrik,d 1975-u Karolinska Institutet4 aut0 (Swepub:oru)hiln |
700 | 1 | a Lichtenstein, Paulu Karolinska Institutet4 aut |
700 | 1 | a D'Onofrio, Brian M.u Department of Psychological and Brain Sciences, Indiana University Bloomington, Bloomington, USA4 aut |
710 | 2 | a Karolinska Institutetb Department of Psychological and Brain Sciences, Indiana University Bloomington, Bloomington, USA4 org |
773 | 0 | t Annals of Epidemiologyd New York, USA : Elsevierg 24:9, s. 629-634.e1q 24:9<629-634.e1x 1047-2797x 1873-2585 |
856 | 4 | u https://europepmc.org/articles/pmc4135008?pdf=render |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-54591 |
856 | 4 8 | u https://doi.org/10.1016/j.annepidem.2014.05.010 |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:129601934 |
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