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Disease course of i...
Disease course of inflammatory bowel disease unclassified in a European population-based inception cohort : an Epi-IBD study
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- Burisch, Johan (författare)
- Department of gastroenterology, North Zealand Hospital, University of Copenhagen, Denmark
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- Chetcuti Zammit, Stefania (författare)
- Division of Gastroenterology, Mater Dei Hospital, Msida, Malta
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- Ellul, Pierre (författare)
- Division of Gastroenterology, Mater Dei Hospital, Msida, Malta
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- Turcan, Svetlana (författare)
- Department of Gastroenterology, State University of Medicine and Pharmacy of the Republic of Moldova, Chisinau, Republic of Moldova
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- Duricova, Dana (författare)
- IBD clinical and research centre, ISCARE., Prague, Czech Republic
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- Bortlik, Martin (författare)
- IBD clinical and research centre, ISCARE., Prague, Czech Republic; Institute of Pharmacology, 1st Faculty of Medicine, Charles University in Prague, Prague
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- Winther Andersen, Karina (författare)
- Medical Department, Regional Hospital of Viborg, Viborg, Denmark
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- Andersen, Vibeke (författare)
- Medical Department, Regional Hospital of Viborg, Viborg, Denmark; Focused research unit for Molecular Diagnostic and Clinical Research (MOK), IRS-Center Sonderjylland, Hospital of Southern Jutland, Aabenraa, Denmark; Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark
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- Kaimakliotis, Ioannis P. (författare)
- Nicosia private practice, Nicosia, Cyprus
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- Fumery, Mathurin (författare)
- Gastroenterology Unit, Epimad Registry, CHU Amiens Sud, Avenue Laennec-Salouel, Amiens University Hospital, Amiens, France
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- Gower-Rousseau, Corinne (författare)
- Public Health, Epidemiology and Economic Health, Registre Epimad, Lille University and Hospital, Lille, France; Lille Inflammation Research International Center LIRIC, Lille University, Lille, France
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- Girardin, Giulia (författare)
- Department of Surgical, Oncological and gastroenterological Sciences, Azienda, University of Padua, Padua, Italy
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- Valpiani, Daniela (författare)
- U.O. Gastroenterologia ed Endoscopia digestiva, Hospital Morgagni Pierantoni, Forlì, Italy
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- Goldis, Adrian (författare)
- Clinic of Gastroenterology, University of Medicine 'Victor Babes', Timisoara, Romania
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- Brinar, Marko (författare)
- Division of Gastroenterology and Hepatology, University Hospital Center Zagreb, Zagreb, Croatia
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- Čuković-Čavka, Silvija (författare)
- Division of Gastroenterology and Hepatology, University Hospital Center Zagreb, Zagreb, Croatia
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- Oksanen, Pia (författare)
- Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland; University of Tampere, Tampere, Finland
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- Collin, Pekka (författare)
- Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland; University of Tampere, Tampere, Finland
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- Barros, Luisa (författare)
- Department of Gastroenterology, Centro Hospitalar de São João EPE, Porto, Portugal
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- Magro, Fernando (författare)
- Department of Gastroenterology, Centro Hospitalar de São João EPE, Porto, Portugal; Department of Biomedicine, Institute of Pharmacology, Faculty of Medicine of Porto University, Porto, Portugal
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- Misra, Ravi (författare)
- IBD Department, St Marks Hospital, Imperial College London, London, UK
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- Arebi, Naila (författare)
- IBD Department, St Marks Hospital, Imperial College London, London, UK
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- Eriksson, Carl, 1981- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Gastroenterology
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- Halfvarson, Jonas, 1970- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Gastroenterology
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- Kievit, Hendrika Adriana Linda (författare)
- Department of Medicine, Herning Central Hospital, Herning, Denmark
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- Pedersen, Natalia (författare)
- Gastroenterology Department, Slagelse Hospital, Slagelse, Denmark
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- Kjeldsen, Jens (författare)
- Gastroenterology Department, Odense University Hospital, Odense, Denmark
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- Myers, Sally (författare)
- IBD Unit, Hull & East Yorkshire NHS Trust, Hull, UK
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- Sebastian, Shaji (författare)
- IBD Unit, Hull & East Yorkshire NHS Trust, Hull, UK
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- Katsanos, Konstantinos H. (författare)
- Department of Gastroenterology, University Hospital of Ioannina, Ioannina, Greece
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- Christodoulou, Dimitrios K. (författare)
- Department of Gastroenterology, University Hospital of Ioannina, Ioannina, Greece
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- Midjord, Jóngerð (författare)
- Medical Department, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands
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- Nielsen, Kári Rubek (författare)
- Medical Department, The National Hospital of the Faroe Islands, Torshavn, Faroe Islands
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- Kiudelis, Gediminas (författare)
- Institute for Digestive Research, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
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- Kupcinskas, Limas (författare)
- Institute for Digestive Research, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania; Department of Gastroenterology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
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- Nikulina, Inna (författare)
- Department of Gastroenterology, Moscow Regional Research Clinical Institute, Moscow, Russian Federation
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- Belousova, Elena (författare)
- Department of Gastroenterology, Moscow Regional Research Clinical Institute, Moscow, Russian Federation
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- Schwartz, Doron (författare)
- Department of Gastroenterology and Hepatology, Soroka Medical Center and Ben Gurion University of the Negev, Beer Sheva, Israel
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- Odes, Selwyn (författare)
- Department of Gastroenterology and Hepatology, Soroka Medical Center and Ben Gurion University of the Negev, Beer Sheva, Israel
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- Salupere, Riina (författare)
- Department of Gastroenterology and Hepatology, Soroka Medical Center and Ben Gurion University of the Negev, Beer Sheva, Israel
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- Carmona, Amalia (författare)
- Department of Gastroenterology. Hospital POVISA, Vigo, Spain
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- Pineda, Juan R. (författare)
- Department of Gastroenterology. Hospital Alvaro Cunqueiro, Instituto Investigación Sanitaria Galicia Sur, EOXI de Vigo, Vigo, Spain
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- Vegh, Zsuzsanna (författare)
- 1st Department of Medicine, Semmelweis University, Budapest, Hungary
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- Lakatos, Peter L. (författare)
- 1st Department of Medicine, Semmelweis University, Budapest, Hungary; Division of Gastroenterology, McGill University Health Center, Montreal, Canada
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- Langholz, Ebbe (författare)
- Department of Gastroenterology, Herlev and Gentofte Hospital, University of Copenhagen, Denmark
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- Munkholm, Pia (författare)
- Department of gastroenterology, North Zealand Hospital, University of Copenhagen, Denmark
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Epi-IBD, group (författare)
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(creator_code:org_t)
- 2019-01-21
- 2019
- Engelska.
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Ingår i: Journal of Gastroenterology and Hepatology. - : John Wiley & Sons. - 0815-9319 .- 1440-1746. ; 34:6, s. 996-1003
- Relaterad länk:
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https://findresearch...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND: A definitive diagnosis of Crohn's disease (CD) or ulcerative colitis (UC) is not always possible and a proportion of patients will be diagnosed as inflammatory bowel disease unclassified (IBDU). The aim of the study was to investigate the prognosis of patients initially diagnosed with IBDU and the disease course during the following five years.METHODS: The Epi-IBD study is a prospective population-based cohort of 1,289 IBD patients diagnosed in centres across Europe. Clinical data were captured prospectively throughout the follow-up period.RESULTS: Overall, 476 (37%) patients were initially diagnosed with CD, 701 (54%) with UC, and 112 (9%) with IBDU. During follow-up, 28 (25%) IBDU patients were changed diagnoses to either UC (n=20, 71%) or CD (n=8, 29%) after a median of six months (IQR: 4-12), while 84 (7% of the total cohort) remained IBDU. A total of 17 (15%) IBDU patients were hospitalized for their IBD during follow-up, while 8 (7%) patients underwent surgery. Most surgeries (n=6, 75%) were performed on patients whose diagnosis was later changed to UC; three of these colectomies led to a definitive diagnosis of UC. Most patients (n=107, 96%) received 5-aminosalicylic acid, while 11 (10%) patients received biologicals, of whom five remained classified as IBDU.CONCLUSIONS: In a population-based inception cohort, 7% of IBD patients were not given a definitive diagnosis of IBD after five years of follow-up. One in four patients with IBDU eventually were classified as CD or UC. Overall, the disease course and medication burden in IBDU patients were mild.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Nyckelord
- Inflammatory bowel disease unclassified
- prognosis
- treatment
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Burisch, Johan
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Chetcuti Zammit, ...
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Ellul, Pierre
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Turcan, Svetlana
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Duricova, Dana
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Bortlik, Martin
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Winther Andersen ...
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Andersen, Vibeke
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Kaimakliotis, Io ...
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Fumery, Mathurin
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Gower-Rousseau, ...
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Girardin, Giulia
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Valpiani, Daniel ...
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Goldis, Adrian
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Brinar, Marko
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Čuković-Čavka, S ...
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Oksanen, Pia
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Collin, Pekka
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Barros, Luisa
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Magro, Fernando
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Misra, Ravi
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Arebi, Naila
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Eriksson, Carl, ...
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Halfvarson, Jona ...
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Kievit, Hendrika ...
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Pedersen, Natali ...
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Kjeldsen, Jens
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Myers, Sally
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Sebastian, Shaji
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Katsanos, Konsta ...
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Christodoulou, D ...
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Midjord, Jóngerð
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Nielsen, Kári Ru ...
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Kiudelis, Gedimi ...
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Kupcinskas, Lima ...
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Nikulina, Inna
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Belousova, Elena
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Schwartz, Doron
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Odes, Selwyn
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Salupere, Riina
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Carmona, Amalia
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Pineda, Juan R.
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Vegh, Zsuzsanna
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Lakatos, Peter L ...
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Langholz, Ebbe
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Munkholm, Pia
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Epi-IBD, group
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Journal of Gastr ...
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Örebro universitet