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The frequency and i...
The frequency and influence of dementia risk factors in prodromal Alzheimer's disease
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- Bos, Isabelle (författare)
- Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, Netherlands
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- Vos, Stephanie J. (författare)
- Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, Netherlands
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- Frölich, Lutz (författare)
- Department of Geriatric Psychiatry, Zentralinstitut für Seelische Gesundheit, University of Heidelberg, Mannheim, Germany
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visa fler...
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- Kornhuber, Johannes (författare)
- Department of Psychiatry and Psychotherapy, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany
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- Wiltfang, Jens (författare)
- Department of Psychiatry and Psychotherapy, University Medical Center (UMC), Georg-August-University, Göttingen, Germany
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- Maier, Wolfgang (författare)
- Department of Psychiatry and Psychotherapy, University of Bonn, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany
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- Peters, Oliver (författare)
- Department of Psychiatry and Psychotherapy, Charité Berlin, Berlin, Germany,Charité - University Medicine Berlin
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- Rüther, Eckhart (författare)
- Department of Psychiatry and Psychotherapy, University of Göttingen, Göttingen, Germany
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- Engelborghs, Sebastiaan (författare)
- Department of Neurology and Memory Clinic, Hospital Network Antwerp (ZNA) Middelheim and Hoge Beuken, Antwerp, Belgium; Reference Center for Biological Markers of Dementia (BIODEM), University of Antwerp, Antwerp, Belgium
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- Niemantsverdriet, Ellis (författare)
- Reference Center for Biological Markers of Dementia (BIODEM), University of Antwerp, Antwerp, Belgium
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- De Roeck, Ellen Elisa (författare)
- Reference Center for Biological Markers of Dementia (BIODEM), University of Antwerp, Antwerp, Belgium; Department of Clinical and Lifespan Psychology, Vrije Universiteit Brussel, Brussels, Belgium,Vrije Universiteit Brussel (VUB)
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- Tsolaki, Magda (författare)
- 3rd Department of Neurology, Aristotle University of Thessaloniki, Memory and Dementia Center, “G Papanicolau” General Hospital, Thessaloniki, Greece
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- Freund-Levi, Yvonne, 1956- (författare)
- Karolinska Institute,Karolinska University Hospital
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- Johannsen, Peter (författare)
- Danish Dementia Research Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
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- Vandenberghe, Rik (författare)
- Department of Neurology, University of Hospital Leuven, Leuven, Belgium; Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Belgium,Catholic University of Leuven
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- Lleó, Alberto (författare)
- Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
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- Alcolea, Daniel (författare)
- Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
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- Frisoni, Giovanni B. (författare)
- Geneva Neuroscience Center, University Hospital and University of Geneva, Geneva, Switzerland; IRCCS San Giovanni di Dio Fatebenefratelli, Brescia, Italy
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- Galluzzi, Samantha (författare)
- IRCCS San Giovanni di Dio Fatebenefratelli, Brescia, Italy,Centro San Giovanni di Dio Fatebenefratelli
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- Nobili, Flavio (författare)
- Clinical Neurology, Department of Neurosciences (DINOGMI), University of Genoa and IRCCS AOU San Martino-IST, Genoa, Italy,Ospedale Policlinico San Martino
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- Morbelli, Silvia (författare)
- Nuclear Medicine, Department of Health Science (DISSAL), University of Genoa IRCCS AOU San Martino-IST, Genoa, Italy,Ospedale Policlinico San Martino
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- Drzezga, Alexander (författare)
- Department of Nuclear Medicine, University of Cologne, Cologne, Germany
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- Didic, Mira (författare)
- AP-HM Hôpitaux de la Timone, Service de Neurologie et Neuropsychologie, Marseille, France; Aix-Marseille Université, INSERM, Institut de Neurosciences des Systèmes, Marseille, France,La Timone University Hospital
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- van Berckel, Bart N. (författare)
- Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, the Netherlands,Amsterdam UMC - Vrije Universiteit Amsterdam
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- Salmon, Eric (författare)
- Department of Neurology and Memory Clinic, CHU Liège, Liège, Belgium; GIGA-CRC in vivo Imaging, University of Liège, Liège, Belgium,University of Liège Hospital
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- Bastin, Christine (författare)
- GIGA-CRC in vivo Imaging, University of Liège, Liège, Belgium
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- Dauby, Solene (författare)
- Department of Neurology and Memory Clinic, CHU Liège, Liège, Belgium,University of Liège Hospital
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- Santana, Isabel (författare)
- Department of Neurology and Memory Clinic, CHU Liège, Liège, Belgium,University of Liège Hospital
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- Baldeiras, Inês (författare)
- Center for Neuroscience and Cell Biology, Faculty of Medicine, Department of Neurology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal,University Hospital of Coimbra
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- de Mendonça, Alexandre (författare)
- Institute of Molecular Medicine and Faculty of Medicine, University of Lisbon, Portugal
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- Silva, Dina (författare)
- Institute of Molecular Medicine and Faculty of Medicine, University of Lisbon, Portugal
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- Wallin, Anders, 1950 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
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- Nordlund, Arto, 1962 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
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- Coloma, Preciosa M. (författare)
- Real World Data Science (RWD-S) Neuroscience and Established Products, F. Hoffmann-La Roche Ltd. Pharmaceuticals Division, Basel, Switzerland
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- Wientzek, Angelika (författare)
- PDB RWD (Real World Data) Team, Roche Products Limited, Welwyn Garden City, UK; Epidemiologische Beratung und Literatur-Recherche “conepi”, Herrsching, Germany
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- Alexander, Myriam (författare)
- PDB RWD (Real World Data) Team, Roche Products Limited, Welwyn Garden City, UK
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- Novak, Gerald P. (författare)
- Janssen Pharmaceutical Research and Development, Titusville, NJ, USA
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- Gordon, Mark Forrest (författare)
- Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT, USA
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- Wallin, Åsa K. (författare)
- Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups
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- Hampel, Harald (författare)
- Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, AXA Research Fund & UPMC Chair, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A), Paris, France; Institut du Cerveau et de la Moelle épinière (ICM), Département de Neurologie, Hôpital de la Pitié-Salpétrière, Paris, France
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- Soininen, Hilkka (författare)
- Institute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland; Neurocenter, Neurology, Kuopio University Hospital, Kuopio, Finland
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- Herukka, Sanna-Kaisa (författare)
- Institute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland; Neurocenter, Neurology, Kuopio University Hospital, Kuopio, Finland
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- Scheltens, Philip (författare)
- Alzheimer Center & Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, Netherlands,Amsterdam UMC - Vrije Universiteit Amsterdam
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- Verhey, Frans R. (författare)
- Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, Netherlands
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- Visser, Pieter Jelle (författare)
- Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, Netherlands; Alzheimer Center & Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, Netherlands,Amsterdam UMC - Vrije Universiteit Amsterdam
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Alzheimer's Disease Neuroimaging Initiative, the (bidragsgivare)
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(creator_code:org_t)
- Elsevier, 2017
- 2017
- Engelska.
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Ingår i: Neurobiology of Aging. - : Elsevier. - 0197-4580 .- 1558-1497. ; 56, s. 33-40
- Relaterad länk:
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https://repository.u...
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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https://lup.lub.lu.s...
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https://gup.ub.gu.se...
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Abstract
Ämnesord
Stäng
- We investigated whether dementia risk factors were associated with prodromal Alzheimer's disease (AD) according to the International Working Group-2 and National Institute of Aging-Alzheimer's Association criteria, and with cognitive decline. A total of 1394 subjects with mild cognitive impairment from 14 different studies were classified according to these research criteria, based on cognitive performance and biomarkers. We compared the frequency of 10 risk factors between the subgroups, and used Cox-regression to examine the effect of risk factors on cognitive decline. Depression, obesity, and hypercholesterolemia occurred more often in individuals with low-AD-likelihood, compared with those with a high-AD-likelihood. Only alcohol use increased the risk of cognitive decline, regardless of AD pathology. These results suggest that traditional risk factors for AD are not associated with prodromal AD or with progression to dementia, among subjects with mild cognitive impairment. Future studies should validate these findings and determine whether risk factors might be of influence at an earlier stage (i.e., preclinical) of AD.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Geriatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Geriatrics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Nyckelord
- Alzheimer's disease
- Biomarkers
- IWG-2 criteria
- NIA-AA criteria
- Prognosis
- Risk factors
- Alzheimer's disease
- Biomarkers
- IWG-2 criteria
- NIA-AA criteria
- Prognosis
- Risk factors
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Bos, Isabelle
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Vos, Stephanie J ...
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Frölich, Lutz
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Kornhuber, Johan ...
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Wiltfang, Jens
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Maier, Wolfgang
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visa fler...
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Peters, Oliver
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Rüther, Eckhart
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Engelborghs, Seb ...
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Niemantsverdriet ...
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De Roeck, Ellen ...
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Tsolaki, Magda
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Freund-Levi, Yvo ...
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Johannsen, Peter
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Vandenberghe, Ri ...
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Lleó, Alberto
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Alcolea, Daniel
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Frisoni, Giovann ...
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Galluzzi, Samant ...
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Nobili, Flavio
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Morbelli, Silvia
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Drzezga, Alexand ...
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Didic, Mira
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van Berckel, Bar ...
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Salmon, Eric
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Bastin, Christin ...
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Dauby, Solene
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Santana, Isabel
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Baldeiras, Inês
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de Mendonça, Ale ...
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Silva, Dina
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Wallin, Anders, ...
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Nordlund, Arto, ...
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Coloma, Preciosa ...
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Wientzek, Angeli ...
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Alexander, Myria ...
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Novak, Gerald P.
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Gordon, Mark For ...
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Wallin, Åsa K.
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Hampel, Harald
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Soininen, Hilkka
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Herukka, Sanna-K ...
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Scheltens, Phili ...
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Verhey, Frans R.
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Visser, Pieter J ...
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Alzheimer's Dise ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Neurologi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Geriatrik
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Psykiatri
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Medicinska och f ...
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och Neurovetenskaper
- Artiklar i publikationen
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Neurobiology of ...
- Av lärosätet
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Örebro universitet
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Karolinska Institutet
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Lunds universitet
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Göteborgs universitet