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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 07272naa a2200553 4500 | |
| 001 | oai:DiVA.org:oru-75201 | |
| 003 | SwePub | |
| 008 | 190726s2019 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:141162731 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-752012 URI |
| 024 | 7 | a https://doi.org/10.1016/j.chemosphere.2019.04.1272 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1411627312 URI |
| 040 | a (SwePub)orud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Guo, Jianqiuu School of Public Health/Key Laboratory of Public Health Safety of Ministry of Education/Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China4 aut |
| 245 | 1 0 | a Anthropometric measures at age 3 years in associations with prenatal and postnatal exposures to chlorophenols |
| 264 | 1 | b Elsevier,c 2019 |
| 338 | a print2 rdacarrier | |
| 500 | a Funding Agencies:National Natural Science Foundation of China NSFC-STINT 81611130087 Natural Science Foundation of Shanghai, China 18ZR1404200 Shanghai Municipal Health Commission 201640037 Shanghai "3-Year Action" Project GWIV-27.3 | |
| 520 | a Background: Chlorophenols (CPs), suspected as endocrine disrupting chemicals, exposure during early life may contribute to body size. However, limited human data with inconsistent findings have examined the developmental effects of CPs exposure.Objective: To explore associations between prenatal and postnatal CPs exposure and anthropometric parameters in children aged 3 years.Methods: A subset of 377 mother-child pairs with urinary five CP concentrations were enrolled from a prospective birth cohort. Generalized linear models were conducted to evaluate associations of CPs exposure with children's anthropometric measures.Results: Maternal urinary 2,4,6-trichlorophenol (2,4,6-TCP) concentrations were significantly negatively associated with weight z scores [regression coefficient (beta)=-0.51, 95% confidence interval (Cl): -0.96, -0.05; p = 0.01], weight for height z scores (beta = -0.54, 95% Cl:-1.02, -0.06; p= 0.01) and body mass index (BMI) z scores (beta = -0.53, 95% CI;-1.03, 0.03; p = 0.01) of children aged 3 years, after adjustment for potential confounders and postnatal CPs exposure. In the sex-stratified analyses, these inverse associations remained among boys, while in girls, positive associations of prenatal 2,4,6-TCP exposure with weight for height z scores and BMI z scores were observed. Postnatal exposure to 2,5-diclorophenol (2,5-DCP) was positively associated with weight z scores (beta = 0.26, 95% CI: 0.02, 0.50; p = 0.04), after controlling for possible confounders and maternal CPs exposure during pregnancy. Considering potential sex-specific effects, these associations were only observed in girls.Conclusions: Our findings indicate that prenatal 2,4,6-TCP exposure and postnatal 2,5-DCP exposure may have adverse and sex-specific effects on children's physical development. | |
| 650 | 7 | a NATURVETENSKAPx Geovetenskap och miljövetenskapx Miljövetenskap0 (SwePub)105022 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Earth and Related Environmental Sciencesx Environmental Sciences0 (SwePub)105022 hsv//eng |
| 653 | a Chlorophenols | |
| 653 | a Prenatal exposure | |
| 653 | a Childhood exposure | |
| 653 | a Anthropometric measures | |
| 653 | a Prospective birth cohort | |
| 700 | 1 | a Wu, Chunhuau School of Public Health/Key Laboratory of Public Health Safety of Ministry of Education/Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China4 aut |
| 700 | 1 | a Zhang, Jimingu School of Public Health/Key Laboratory of Public Health Safety of Ministry of Education/Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China4 aut |
| 700 | 1 | a Jiang, Shuaiu School of Public Health/Key Laboratory of Public Health Safety of Ministry of Education/Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China4 aut |
| 700 | 1 | a Lv, Shenliangu School of Public Health/Key Laboratory of Public Health Safety of Ministry of Education/Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China4 aut |
| 700 | 1 | a Lu, Dashengu Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China4 aut |
| 700 | 1 | a Qi, Xiaojuanu School of Public Health/Key Laboratory of Public Health Safety of Ministry of Education/Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China; Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China4 aut |
| 700 | 1 | a Feng, Chaou Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China4 aut |
| 700 | 1 | a Liang, Weijiuu Changning District Center for Disease Control and Prevention, Shanghai, China4 aut |
| 700 | 1 | a Chang, Xiuliu School of Public Health/Key Laboratory of Public Health Safety of Ministry of Education/Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China4 aut |
| 700 | 1 | a Zhang, Yubinu School of Public Health/Key Laboratory of Public Health Safety of Ministry of Education/Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China4 aut |
| 700 | 1 | a Xu, Haou Changning District Center for Disease Control and Prevention, Shanghai, China4 aut |
| 700 | 1 | a Cao, Yang,c Associate Professor,d 1972-u Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Unit of Biostatistics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden4 aut0 (Swepub:oru)yco |
| 700 | 1 | a Wang, Guoquanu Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China4 aut |
| 700 | 1 | a Zhou, Zhijunu School of Public Health/Key Laboratory of Public Health Safety of Ministry of Education/Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, China4 aut |
| 710 | 2 | a School of Public Health/Key Laboratory of Public Health Safety of Ministry of Education/Key Lab of Health Technology Assessment, National Health Commission of the People's Republic of China, Fudan University, Shanghai, Chinab Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China4 org |
| 773 | 0 | t Chemosphered : Elsevierg 228, s. 204-211q 228<204-211x 0045-6535x 1879-1298 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-75201 |
| 856 | 4 8 | u https://doi.org/10.1016/j.chemosphere.2019.04.127 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:141162731 |
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