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Prestroke Mobility ...
Prestroke Mobility and Dementia as Predictors of Stroke Outcomes in Patients Over 65 Years of Age : A Cohort Study From The Swedish Dementia and Stroke Registries
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- Garcia-Ptacek, Sara (författare)
- Karolinska Institutet
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- Contreras Escamez, Beatriz (författare)
- Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Clinical Geriatrics, Karolinska Institutet, Huddinge, Sweden; Department of Geriatrics, Hospital Universitario de Getafe, Madrid, Spain
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- Zupanic, Eva (författare)
- Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Karolinska Institutet, Huddinge, Sweden; Department of Neurology, University Medical Center, Ljubljana, Slovenia
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- Religa, Dorota (författare)
- Karolinska Institutet
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- von Koch, Lena (författare)
- Karolinska Institutet
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- Johnell, Kristina (författare)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)
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- von Euler, Mia, 1967- (författare)
- Karolinska Institutet
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- Kåreholt, Ingemar, 1960- (författare)
- Karolinska Institutet,Stockholms universitet,Jönköping University,HHJ, Institutet för gerontologi,HHJ. ARN-J (Aging Research Network - Jönköping),Aging Research Center (ARC), Karolinska Institutet and Stockholm University, Stockholm, Sweden,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Jönköping University, Sweden
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- Eriksdotter, Maria (författare)
- Karolinska Institutet
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(creator_code:org_t)
- Hagerstown, Maryland : Lippincott Williams & Wilkins, 2018
- 2018
- Engelska.
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Ingår i: Journal of the American Medical Directors Association. - Hagerstown, Maryland : Lippincott Williams & Wilkins. - 1525-8610 .- 1538-9375. ; 19:2, s. 154-161
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Abstract
Ämnesord
Stäng
- OBJECTIVES: To explore the association between prestroke mobility dependency and dementia on functioning and mortality outcomes after stroke in patients>65 years of age.DESIGN: Longitudinal cohort study based on SveDem, the Swedish Dementia Registry and Riksstroke, the Swedish Stroke Registry.PARTICIPANTS: A total of 1689 patients with dementia >65 years of age registered in SveDem and suffering a first stroke between 2007 and 2014 were matched with 7973 controls without dementia with stroke.MEASUREMENTS: Odds ratios (ORs) and 95% confidence intervals (CIs) for intrahospital mortality, and functioning and mortality outcomes at 3 months were calculated. Functioning included level of residential assistance (living at home without help, at home with help, or nursing home) and mobility dependency (independent, needing help to move outdoors, or needing help indoors and outdoors).RESULTS: Prestroke dependency in activities of daily living and mobility were worse in patients with dementia than controls without dementia. In unadjusted analyses, patients with dementia were more often discharged to nursing homes (51% vs 20%; P < .001). Mortality at 3 months was higher in patients with dementia (31% vs 23% P < .001) and fewer were living at home without help (21% vs 55%; P < .001). In adjusted analyses, prestroke dementia was associated with higher risk of 3-month mortality (OR 1.34; 95% CI 1.18-1.52), requiring a higher level of residential assistance (OR 4.07; 3.49-.75) and suffering from more dependency in relation to mobility (OR 2.57; 2.20-3.02). Patients with dementia who were independent for mobility prestroke were more likely to be discharged to a nursing home compared with patients without dementia with the same prestroke mobility (37% vs 16%; P < .001), but there were no differences in discharge to geriatric rehabilitation (19% for both; P = .976). Patients, who moved independently before stroke, were more often discharged home (60% vs 28%) and had lower mortality. In adjusted analyses, prestroke mobility limitations were associated with higher odds for poorer mobility, needing more residential assistance, and death.CONCLUSIONS: Patients with mobility impairments and/or dementia present a high burden of disability after a stroke. There is a need for research on stroke interventions among these populations.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Geriatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Geriatrics (hsv//eng)
Nyckelord
- Stroke
- dementia
- frailty
- functioning
- mobility
- mortality
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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