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Psychological burde...
Psychological burden in the era of Haart : Impact of selenium therapy
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- Shor-Posner, G. (författare)
- Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
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- Lecusay, Robert, 1974- (författare)
- Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
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- Miguez, M. J. (författare)
- Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
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- Moreno-Black, G. (författare)
- Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
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- Zhang, G. Y. (författare)
- Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
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- Rodriguez, N. (författare)
- Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
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- Burbano, X. (författare)
- Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
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- Baum, M. (författare)
- Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
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- Wilkie, F. (författare)
- Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
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Dept of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States (creator_code:org_t)
- Sage Publications, 2003
- 2003
- Engelska.
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Ingår i: International Journal of Psychiatry in Medicine. - : Sage Publications. - 0091-2174 .- 1541-3527. ; 33:1, s. 55-69
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.2...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Objective: To determine the impact of nutritional (selenium) chemoprevention on levels of psychological burden (anxiety, depression, and mood state) in HIV/AIDS. Method: A randomized, double-blind, placebo-controlled selenium therapy (200 mug/day) trial was conducted in HIV+ drug users from 1998-2000. Psychosocial measures (STAI-State and Trait anxiety, BDI-depression, and POMS- mood state), clinical status (CD4 cell count, viral load), and plasma selenium levels were determined at baseline and compared with measurements obtained at the 12-month evaluation in 63 participants (32 men, 31 women). Results: The majority of the study participants reported elevated levels of both State (68%) and Trait (70%) anxiety. Approximately 25% reported overall mood distress (POMS > 60) and moderate depression (BDI > 20). Psychological burden was not influenced by current drug use, antiretroviral treatment, or viral load. At the 12-month evaluation, participants who received selenium reported increased vigor (p = 0.004) and had less anxiety (State, p = 0.05 and Trait, p = 0.02), compared to the placebo-treated individuals. No apparent selenium-related affect on depression or distress was observed. The risk for state anxiety was almost four times higher, and nearly nine times greater for trait anxiety in the placebo-treated group, controlling for antiretroviral therapy, CD4 cell decline (> 50 cells) and years of education. Conclusions: Selenium therapy may be a beneficial treatment to decrease anxiety in HIV+ drug users who exhibit a high prevalence of psychological burden.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Nyckelord
- anxiety
- HIV infection
- selenium
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- ref (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Shor-Posner, G.
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Lecusay, Robert, ...
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Miguez, M. J.
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Moreno-Black, G.
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Zhang, G. Y.
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Rodriguez, N.
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visa fler...
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Burbano, X.
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Baum, M.
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Wilkie, F.
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Psykiatri
- Artiklar i publikationen
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International Jo ...
- Av lärosätet
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Södertörns högskola
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Jönköping University