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Consumption of soft...
Consumption of soft drinks and juices and risk of liver and biliary tract cancers in a European cohort
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- Stepien, Magdalena (författare)
- International Agency for Research on Cancer, World Health Organization
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- Duarte-Salles, Talita (författare)
- International Agency for Research on Cancer, World Health Organization
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- Fedirko, Veronika (författare)
- Emory University Rollins School of Public Health,International Agency for Research on Cancer, World Health Organization
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- Trichopoulou, Antonia (författare)
- Hellenic Health Foundation, Athens,National and Kapodistrian University of Athens
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- Lagiou, Pagona (författare)
- National and Kapodistrian University of Athens,Harvard University
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- Bamia, Christina (författare)
- National and Kapodistrian University of Athens
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- Overvad, Kim (författare)
- Aarhus University
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- Tjønneland, Anne (författare)
- Danish Cancer Society
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- Hansen, Louise (författare)
- Danish Cancer Society
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- Boutron-Ruault, Marie-Christine (författare)
- Institut Gustave Roussy,National Institute for Health and Medical Research, France,University of Paris-Saclay
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- Fagherazzi, Guy (författare)
- National Institute for Health and Medical Research, France,Institut Gustave Roussy,University of Paris-Saclay
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- Severi, Gianluca (författare)
- Cancer Council Victoria,University of Melbourne
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- Kühn, Tilman (författare)
- German Cancer Research Centre
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- Kaaks, Rudolf (författare)
- German Cancer Research Centre
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- Aleksandrova, Krasimira (författare)
- German Institute of Human Nutrition
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- Boeing, Heiner (författare)
- German Institute of Human Nutrition
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- Klinaki, Eleni (författare)
- Hellenic Health Foundation, Athens
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- Palli, Domenico (författare)
- Cancer Research and Prevention Institute (ISPO)
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- Grioni, Sara (författare)
- Istituto Nazionale dei Tumori
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- Panico, Salvatore (författare)
- University of Naples Federico II
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- Tumino, Rosario (författare)
- Civic and M.P Arezzo Hospital
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- Naccarati, Alessio (författare)
- Human Genetics Foundation (HuGeF)
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- Bueno-de-Mesquita, H. Bas (författare)
- University Medical Center Utrecht,Imperial College London,National Institute for Public Health and the Environment (RIVM)
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- Peeters, Petra H. (författare)
- University Medical Center Utrecht
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- Skeie, Guri (författare)
- UiT The Arctic University of Norway, Tromsø
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- Weiderpass, Elisabete (författare)
- Karolinska Institute,Karolinska Institutet,UiT The Arctic University of Norway, Tromsø,Folkhälsan Research Center,Cancer Registry of Norway, Institute of Population-Based Cancer Research
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- Parr, Christine L. (författare)
- Norwegian Institute of Public Health
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- Quirós, José Ramón (författare)
- Public Health Directorate
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- Buckland, Genevieve (författare)
- Catalan Institute of Oncology
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- Molina-Montes, Esther (författare)
- Murcia Regional Health Authority
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- Amiano, Pilar (författare)
- CIBER Epidemiology and Public Health (CIBERESP),Biodonostia Health Research Institute
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- Chirlaque, Maria-Dolores (författare)
- CIBER Epidemiology and Public Health (CIBERESP),Murcia Regional Health Authority
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- Ardanaz, Eva (författare)
- CIBER Epidemiology and Public Health (CIBERESP),Health Research Institute of Navarra (IDISNA)
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- Sonestedt, Emily (författare)
- Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Nutritionsepidemiologi,Diabetes - Cardiovascular Disease,Lund University Research Groups,Nutrition Epidemiology
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- Ericson, Ulrika (författare)
- Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups
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- Wennberg, Maria (författare)
- Umeå University,Umeå universitet,Näringsforskning
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- Nilsson, Lena Maria, 1965- (författare)
- Umeå University,Umeå universitet,Näringsforskning,Arktiskt centrum vid Umeå universitet (Arcum)
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- Khaw, Kay-Tee (författare)
- University of Cambridge
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- Wareham, Nick (författare)
- University of Cambridge
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- Bradbury, Kathryn E. (författare)
- University of Oxford
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- Ward, Heather A. (författare)
- Imperial College London
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- Romieu, Isabelle (författare)
- International Agency for Research on Cancer, World Health Organization
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- Jenab, Mazda (författare)
- International Agency for Research on Cancer, World Health Organization
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(creator_code:org_t)
- 2014-12-21
- 2016
- Engelska.
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Ingår i: European Journal of Nutrition. - : Springer Science and Business Media LLC. - 1436-6207 .- 1436-6215. ; 55:1, s. 7-20
- Relaterad länk:
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https://europepmc.or...
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- PURPOSE: The aim of the study was to assess associations between intake of combined soft drinks (sugar sweetened and artificially sweetened) and fruit and vegetable juices and the risk of hepatocellular carcinoma (HCC), intrahepatic bile duct (IHBC) and biliary tract cancers (GBTC) using data from the European Prospective Investigation into Cancer and Nutrition cohort of 477,206 participants from 10 European countries.METHODS: After 11.4 years of follow-up, 191 HCC, 66 IHBC and 236 GBTC cases were identified. Hazard ratios and 95 % confidence intervals (HR; 95 % CI) were estimated with Cox regression models with multivariable adjustment (baseline total energy intake, alcohol consumption and intake pattern, body mass index, physical activity, level of educational attainment and self-reported diabetes status).RESULTS: No risk associations were observed for IHBC or GBTC. Combined soft drinks consumption of >6 servings/week was positively associated with HCC risk: HR 1.83; 95 % CI 1.11-3.02, p trend = 0.01 versus non-consumers. In sub-group analyses available for 91 % of the cohort artificially sweetened soft drinks increased HCC risk by 6 % per 1 serving increment (HR 1.06, 95 % CI 1.03-1.09, n cases = 101); for sugar-sweetened soft drinks, this association was null (HR 1.00, 95 % CI 0.95-1.06; n cases = 127, p heterogeneity = 0.07). Juice consumption was not associated with HCC risk, except at very low intakes (<1 serving/week: HR 0.60; 95 % CI 0.38-0.95; p trend = 0.02 vs. non-consumers).CONCLUSIONS: Daily intake of combined soft drinks is positively associated with HCC, but a differential association between sugar and artificially sweetened cannot be discounted. This study provides some insight into possible associations of HCC with sugary drinks intake. Further exploration in other settings is required.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- whole grains
- dietary patterns
- factor analysis
- Scandinavia
- principal component analysis
- Biliary tract cancers
- Fruit and vegetable juice
- Hepatocellular carcinoma
- Prospective cohort
- Soft drink
Publikations- och innehållstyp
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- art (ämneskategori)
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Stepien, Magdale ...
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Duarte-Salles, T ...
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Fedirko, Veronik ...
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Trichopoulou, An ...
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Lagiou, Pagona
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Bamia, Christina
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visa fler...
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Overvad, Kim
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Tjønneland, Anne
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Hansen, Louise
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Boutron-Ruault, ...
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Fagherazzi, Guy
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Severi, Gianluca
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Kühn, Tilman
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Kaaks, Rudolf
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Aleksandrova, Kr ...
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Boeing, Heiner
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Klinaki, Eleni
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Palli, Domenico
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Grioni, Sara
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Panico, Salvator ...
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Tumino, Rosario
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Naccarati, Aless ...
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Bueno-de-Mesquit ...
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Peeters, Petra H ...
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Skeie, Guri
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Weiderpass, Elis ...
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Parr, Christine ...
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Quirós, José Ram ...
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Buckland, Genevi ...
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Molina-Montes, E ...
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Amiano, Pilar
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Chirlaque, Maria ...
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Ardanaz, Eva
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Sonestedt, Emily
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Ericson, Ulrika
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Wennberg, Maria
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Nilsson, Lena Ma ...
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Khaw, Kay-Tee
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Wareham, Nick
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Bradbury, Kathry ...
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Ward, Heather A.
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Romieu, Isabelle
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Jenab, Mazda
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Folkhälsovetensk ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Näringslära
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Cancer och onkol ...
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European Journal ...
- Av lärosätet
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Umeå universitet
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Karolinska Institutet
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Lunds universitet