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Vitamin D status wa...
Vitamin D status was not associated with anxiety, depression, or health-related quality of life in Middle Eastern and African-born immigrants in Sweden
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- Granlund, Lena E., 1960- (författare)
- Umeå universitet,Allmänmedicin
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- Ramnemark, Anna (författare)
- Umeå universitet,Geriatrik
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- Andersson, Christer (författare)
- Umeå universitet,Allmänmedicin
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- Lindkvist, Marie (författare)
- Umeå universitet,Statistik,Institutionen för epidemiologi och global hälsa
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- Norberg, Margareta (författare)
- Umeå universitet,Institutionen för epidemiologi och global hälsa
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- Fhärm, Eva (författare)
- Umeå universitet,Allmänmedicin
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(creator_code:org_t)
- Elsevier, 2020
- 2020
- Engelska.
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Ingår i: Nutrition Research. - : Elsevier. - 0271-5317 .- 1879-0739. ; 75, s. 109-118
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Active vitamin D is a neurosteroid that may modulate brain function. Associations between vitamin D deficiency and depression and anxiety have been demonstrated. We hypothesized that there was an association between anxiety, depression, and health-related quality of life (HRQOL) and vitamin D status. To test this hypothesis, we examined the association between anxiety, depression, and HRQOL and 25-hydroxyvitamin D (25[OH]D) concentrations in the Middle Eastern and African-born immigrant population. All immigrants aged 25-65 years, born in 9 African or Middle Eastern countries, and living in 3 districts in Umea (n = 1306) were invited, with 195 English- or Swedish-speaking immigrants (104 men and 91 women) participated. Anxiety and depression were measured using the Hospital Anxiety and Depression scale. HRQOL was measured using EuroQoL-5 Dimension 3 Level Questionnaire and EuroQoL Visual Analogue Scale. Serum 25(OH)D was measured using liquid chromatography-tandem mass spectrometry. Associations were determined using logistic and linear regression. Analyses were adjusted for sex, age, origin, socioeconomic factors, lifestyle, chronic diseases, and obesity. In total, 71% had 25(OH)D less than 50 nmol/ L and 11% had 25(OH)D less than 25 nmol/L. Anxiety, depression, and HRQOL were not associated with 25(OH)D in the immigrant population. Anxiety was common in female immigrants from the Middle East (32.7%); and after adjustment, lower 25(OH)D concentrations were associated with higher risk of anxiety (25[OH]D <= 49 nmol/L vs 25[OH] D >= 50 nmol/L: odds ratio 23.2 [95% confidence interval 1.97 - 271.9] P = .012) in this subgroup only; however, reverse causality could not be excluded. In conclusion, the study showed no association between depression, anxiety, or HRQOL and vitamin D status in the immigrant population.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- Vitamin D deficiency
- 25(OH)D
- Cross-sectional study
- Anxiety
- Depression
- Health-related quality of life
- Immigrant
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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