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The prepuce :
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Winberg, JanDepartment of Paediatrics, Karolinska Hospital, Karolinska Institutet, Stockholm, Sweden
(författare)
The prepuce : a mistake of nature?
- Artikel/kapitelEngelska1989
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Elsevier Ltd.1989
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LIBRIS-ID:oai:DiVA.org:umu-45383
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-45383URI
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https://doi.org/10.1016/S0140-6736(89)91619-XDOI
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Språk:engelska
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Sammanfattning på:engelska
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Originally published as Volume 1, Issue 8638, 1989. Available online 22 September 2003.
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Retrospective studies suggest that circumcision of newborn boys will reduce the frequency of male early infantile urinary tract infection (UTI) by about 90%. If they are correct, this will be the first known instance of a common potentially lethal disease being preventable by extirpation of a piece of normal tissue. To reconcile the phenomenon with existing views of evolution and biology, it is suggested that the effects of one unphysiological intervention are counterbalancing those of another--ie, colonisation of the baby's gastrointestinal tract and genitals in maternity units by Escherichia coli strains of non-maternal origin, to which the baby has no passive immunity. As an alternative to circumcision to prevent early infantile male UTI, more natural colonisation could be promoted by strict rooming-in of mother and baby or by active colonisation of the baby with his mother's anaerobic gut flora.
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Gothefors, Leif,1940-Umeå universitet,Pediatrik(Swepub:umu)lego0001
(författare)
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Bollgren, IngelaDepartment of Paediatrics, Sachs's Children's Hospital, Karolinska Institutet, Stockholm, Sweden
(författare)
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Herthelius, MariaDepartment of Paediatrics, Karolinska Hospital, Karolinska Institutet, Stockholm, Sweden
(författare)
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Tullus, KjellDepartment of Paediatrics, Danderyds Hospital, Stockholm, Sweden
(författare)
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Department of Paediatrics, Karolinska Hospital, Karolinska Institutet, Stockholm, SwedenPediatrik
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:The Lancet: Elsevier Ltd.333:8638, s. 598-5990140-67361474-547X
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