onr:"swepub:oai:DiVA.org:uu-255953"
Sökning: onr:"swepub:oai:DiVA.org:uu-255953" > Is There any Role f...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03118naa a2200361 4500 | |
| 001 | oai:DiVA.org:uu-255953 | |
| 003 | SwePub | |
| 008 | 150621s2015 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:132537859 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2559532 URI |
| 024 | 7 | a https://doi.org/10.1089/ars.2015.64042 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1325378592 URI |
| 040 | a (SwePub)uud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Basu, Samaru Uppsala universitet,Oxidativ stress och inflammation4 aut0 (Swepub:uu)samabasu |
| 245 | 1 0 | a Is There any Role for Serum Cathepsin S, CRP levels on Prognostic Information in Breast Cancer? :b The Swedish Mammography Cohort |
| 264 | 1 | b Mary Ann Liebert Inc,c 2015 |
| 338 | a print2 rdacarrier | |
| 520 | a Breast cancer is the most common cancer among women, and both low-grade inflammation and cathepsins might have important roles in breast cancer. We questioned whether prediagnostic circulating levels of C-reactive protein (CRP), cathepsin B and cathepsin S were associated with breast cancer risk. Sixty-nine incident breast cancer cases diagnosed after blood collection and 719 controls from the Swedish Mammography Cohort were analysed for systemic CRP, cathepsin B and cathepsin S. Cathepsin S and inflammation (hsCRP) adjusted cathepsin S were inversely associated with breast cancer risk (cathepsin S: OR for top vs. bottom tertile = 0.46; 95% CI = 0.23-0.92; Ptrend = 0.02; hsCRP adjusted cathepsin S: OR of 0.44; 95% CI = 0.22-0.87; Ptrend = 0.02). hsCRP was significantly associated with increased breast cancer risk (OR for top vs. bottom tertile= 2.01; 95% CI = 1.02-3.95; Ptrend = 0.04). No significant association was observed between cathepsin B and breast cancer risk (OR for top vs. bottom tertile= 0.67; 95% CI = 0.32-1.40; Ptrend = 0.30). These observations lead to hypothesis that levels of cathepsin S and hsCRP observed in women who later developed breast cancer may provide prognostic information regarding tumor development and need to be evaluated in prospective studies. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
| 700 | 1 | a Harris, Hollyu Karolinska Institutet4 aut |
| 700 | 1 | a Larsson, Andersu Uppsala universitet,Biokemisk struktur och funktion4 aut0 (Swepub:uu)andlarss |
| 700 | 1 | a Vasson, Marie-Paule4 aut |
| 700 | 1 | a Wolk, Alicjau Karolinska Institutet4 aut |
| 710 | 2 | a Uppsala universitetb Oxidativ stress och inflammation4 org |
| 773 | 0 | t Antioxidants and Redox Signalingd : Mary Ann Liebert Incg 23:16, s. 1298-1302q 23:16<1298-1302x 1523-0864x 1557-7716 |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-255953 |
| 856 | 4 8 | u https://doi.org/10.1089/ars.2015.6404 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:132537859 |
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