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Vertebrate sex-dete...
Vertebrate sex-determining genes play musical chairs
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- Pan, Qiaowei (författare)
- INRA, Fish Physiol & Genom Lab, F-35042 Rennes, France
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- Anderson, Jennifer (författare)
- INRA, Fish Physiol & Genom Lab, F-35042 Rennes, France
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- Bertho, Sylvain (författare)
- INRA, Fish Physiol & Genom Lab, F-35042 Rennes, France; Univ Wurzburg, Physiol Chem, Bioctr, D-97074 Wurzburg, Germany
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- Herpin, Amaury (författare)
- INRA, Fish Physiol & Genom Lab, F-35042 Rennes, France
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- Wilson, Catherine (författare)
- Univ Oregon, Inst Neurosci, Eugene, OR 97403 USA
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- Postlethwait, John H. (författare)
- Univ Oregon, Inst Neurosci, Eugene, OR 97403 USA
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- Schartl, Manfred (författare)
- Univ Wurzburg, Physiol Chem, Bioctr, D-97074 Wurzburg, Germany; Univ Hosp, Comprehens Canc Ctr Mainfranken, D-97080 Wurzburg, Germany; Texas A&M Univ, Texas Inst Adv Study, College Stn, TX 77843 USA; Texas A&M Univ, Dept Biol, College Stn, TX 77843 USA
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- Guiguen, Yann (författare)
- INRA, Fish Physiol & Genom Lab, F-35042 Rennes, France
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(creator_code:org_t)
- Elsevier BV, 2016
- 2016
- Engelska.
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Ingår i: Comptes rendus. Biologies. - : Elsevier BV. - 1631-0691 .- 1768-3238. ; 339:7-8, s. 258-262
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Sexual reproduction is one of the most highly conserved processes in evolution. However, the genetic and cellular mechanisms making the decision of whether the undifferentiated gonad of animal embryos develops either towards male or female are manifold and quite diverse. In vertebrates, sex-determining mechanisms range from environmental to simple or complex genetic mechanisms and different mechanisms have evolved repeatedly and independently. In species with simple genetic sex-determination, master sex-determining genes lying on sex chromosomes drive the gonadal differentiation process by switching on a developmental program, which ultimately leads to testicular or ovarian differentiation. So far, very few sex-determining genes have been identified in vertebrates and apart from mammals and birds, these genes are apparently not conserved over a larger number of related orders, families, genera, or even species. To fill this knowledge gap and to better explore genetic sex-determination, we propose a strategy (RAD-Sex) that makes use of next-generation sequencing technology to identify genetic markers that define sex-specific segments of the male or female genome.
Ämnesord
- NATURVETENSKAP -- Biologi -- Evolutionsbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Evolutionary Biology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
Nyckelord
- Sex-determination
- Evolution
- Vertebrates
- Fish
- Next-generation sequencing
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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