Sökning: onr:"swepub:oai:DiVA.org:uu-318284" > Hemorrhagic shock i...
Fältnamn | Indikatorer | Metadata |
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000 | 02446naa a2200289 4500 | |
001 | oai:DiVA.org:uu-318284 | |
003 | SwePub | |
008 | 220116s1985 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3182842 URI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Schoenberg, M H4 aut |
245 | 1 0 | a Hemorrhagic shock in the dog. I. Correlation between survival and severity of shock. |
264 | 1 | c 1985 |
338 | a print2 rdacarrier | |
520 | a A prerequisite elucidating the pathomechanism of hemorrhagic shock are reproducible experimental models, leading to a predictable outcome. Two concepts have been reported to be a good predictor for the outcome both employing a fixed hypotension level: total oxygen deficit and shed blood volume uptake. To correlate these two models we subjected 31 dogs to a standardized hemorrhagic shock procedure. Besides determination of acid-base status, hematocrit, mean arterial pressure, and cardiac output, these two parameters were measured continuously. Seventeen dogs survived the shock procedure, 14 died within 24 h. During shock, neither oxygen deficit nor any other parameter mentioned above correlated with the final outcome of the shock state. The only significant difference between surviving and non-surviving animals during this period was the amount of uptake. The non-surviving dogs exhibited a higher uptake volume, indicating an incipient collapse of the microcirculation. Terminating the duration of hypotension at an uptake volume of 5% of the maximum shed blood, all animals survived, while after an uptake volume of 15% about 50% of the dogs died. Using uptake volumes of various degrees in a hemorrhagic shock model as the endpoint of the hypotensive stress, it seems possible to produce reliable survival rates. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Fysiologi0 (SwePub)301062 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Physiology0 (SwePub)301062 hsv//eng |
700 | 1 | a Smedegård, G4 aut |
700 | 1 | a Gerdin, Bengt,d 1947-4 aut |
700 | 1 | a Messmer, K4 aut |
700 | 1 | a Arfors, K E4 aut |
773 | 0 | t Research in experimental medicineg 185:1, s. 21-33q 185:1<21-33x 0300-9130x 1433-8580 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-318284 |
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