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High prevalence of ...
High prevalence of Seoul hantavirus in a breeding colony of pet rats
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- Mcelhinney, L. M. (författare)
- Anim & Plant Hlth Agcy, Dept Virol, Weybridge, Surrey, England.;Univ Liverpool, HPRU Emerging & Zoonot Infect, Inst Infect & Global Hlth, Liverpool, Merseyside, England.
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- Marston, D. A. (författare)
- Anim & Plant Hlth Agcy, Dept Virol, Weybridge, Surrey, England.
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- Pounder, K. C. (författare)
- Univ Liverpool, HPRU Emerging & Zoonot Infect, Inst Infect & Global Hlth, Liverpool, Merseyside, England.
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- Goharriz, H. (författare)
- Anim & Plant Hlth Agcy, Dept Virol, Weybridge, Surrey, England.
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- Wise, E. L. (författare)
- Anim & Plant Hlth Agcy, Dept Virol, Weybridge, Surrey, England.
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- Verner-Carlsson, Jenny (författare)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi
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- Jennings, D. (författare)
- Anim & Plant Hlth Agcy, Dept Virol, Weybridge, Surrey, England.
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- Johnson, N. (författare)
- Anim & Plant Hlth Agcy, Dept Virol, Weybridge, Surrey, England.
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- Civello, A. (författare)
- APHA, Dept Pathol, Weybridge, Surrey, England.
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- Nunez, A. (författare)
- APHA, Dept Pathol, Weybridge, Surrey, England.
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- Brooks, T. (författare)
- Univ Liverpool, HPRU Emerging & Zoonot Infect, Inst Infect & Global Hlth, Liverpool, Merseyside, England.;Publ Hlth England, Rare & Imported Pathogens Lab, Salisbury, Wilts, England.
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- Breed, A. C. (författare)
- APHA, Dept Epidemiol Sci, Weybridge, Surrey, England.;Dept Agr & Water Resources, Epidemiol & Hlth Sect 1, Canberra, ACT, Australia.
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- Lawes, J. (författare)
- APHA, Dept Epidemiol Sci, Weybridge, Surrey, England.
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- Lundkvist, Åke (författare)
- Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Institutionen för medicinska vetenskaper
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- Featherstone, C. A. (författare)
- APHA, Thirsk Vet Invest Ctr, Thirsk, England.
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- Fooks, A. R. (författare)
- Anim & Plant Hlth Agcy, Dept Virol, Weybridge, Surrey, England.;Univ Liverpool, HPRU Emerging & Zoonot Infect, Inst Infect & Global Hlth, Liverpool, Merseyside, England.
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Anim & Plant Hlth Agcy, Dept Virol, Weybridge, Surrey, England;Univ Liverpool, HPRU Emerging & Zoonot Infect, Inst Infect & Global Hlth, Liverpool, Merseyside, England. Anim & Plant Hlth Agcy, Dept Virol, Weybridge, Surrey, England. (creator_code:org_t)
- 2017
- 2017
- Engelska.
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Ingår i: Epidemiology and Infection. - 0950-2688 .- 1469-4409. ; 145:15, s. 3115-3124
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- As part of further investigations into three linked haemorrhagic fever with renal syndrome (HFRS) cases in Wales and England, 21 rats from a breeding colony in Cherwell, and three rats from a household in Cheltenham were screened for hantavirus. Hantavirus RNA was detected in either the lungs and/or kidney of 17/21 (81%) of the Cherwell rats tested, higher than previously detected by blood testing alone (7/21, 33%), and in the kidneys of all three Cheltenham rats. The partial L gene sequences obtained from 10 of the Cherwell rats and the three Cheltenham rats were identical to each other and the previously reported UK Cherwell strain. Seoul hantavirus (SEOV) RNA was detected in the heart, kidney, lung, salivary gland and spleen (but not in the liver) of an individual rat from the Cherwell colony suspected of being the source of SEOV. Serum from 20/20 of the Cherwell rats and two associated HFRS cases had high levels of SEOV-specific antibodies (by virus neutralisation). The high prevalence of SEOV in both sites and the moderately severe disease in the pet rat owners suggest that SEOV in pet rats poses a greater public health risk than previously considered.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Nyckelord
- Hantavirus
- Rabies (animal)
- Rabies (human)
- Virology (human) and epidemiology
- Zoonoses
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Mcelhinney, L. M ...
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Marston, D. A.
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Pounder, K. C.
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Goharriz, H.
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Wise, E. L.
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Verner-Carlsson, ...
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visa fler...
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Jennings, D.
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Johnson, N.
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Civello, A.
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Nunez, A.
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Brooks, T.
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Breed, A. C.
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Lawes, J.
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Lundkvist, Åke
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Featherstone, C. ...
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Fooks, A. R.
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Infektionsmedici ...
- Artiklar i publikationen
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Epidemiology and ...
- Av lärosätet
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Uppsala universitet