Sökning: onr:"swepub:oai:DiVA.org:uu-382470" >
Simulating DNA Chip...
Simulating DNA Chip Design Using All-Electronic Graphene-Based Substrates
-
- Martins, Ernane de Freitas (författare)
- Uppsala universitet,Materialteori,Sao Paulo State Univ UNESP, Inst Theoret Phys, Campus Sao Paulo, BR-01140070 Sao Paulo, Brazil;Univ Sao Paulo, Inst Phys, Sao Paulo, SP, Brazil
-
- Feliciano, Gustavo Troiano (författare)
- Sao Paulo State Univ UNESP, Inst Chem, Campus Araraquara, BR-14800060 Araraquara, Brazil
-
- Scheicher, Ralph H. (författare)
- Uppsala universitet,Materialteori
-
visa fler...
-
- Rocha, Alexandre Reily (författare)
- Sao Paulo State Univ UNESP, Inst Theoret Phys, Campus Sao Paulo, BR-01140070 Sao Paulo, Brazil
-
visa färre...
-
(creator_code:org_t)
- 2019-03-08
- 2019
- Engelska.
-
Ingår i: Molecules. - : MDPI. - 1431-5157 .- 1420-3049. ; 24:5
- Relaterad länk:
-
https://doi.org/10.3...
-
visa fler...
-
https://uu.diva-port... (primary) (Raw object)
-
https://www.mdpi.com...
-
https://urn.kb.se/re...
-
https://doi.org/10.3...
-
visa färre...
Abstract
Ämnesord
Stäng
- In this paper, we present a theoretical investigation of an all-electronic biochip based on graphene to detect DNA including a full dynamical treatment for the environment. Our proposed device design is based on the changes in the electronic transport properties of graphene interacting with DNA strands under the effect of the solvent. To investigate these systems, we applied a hybrid methodology, combining quantum and classical mechanics (QM/MM) coupled to non-equilibrium Green's functions, allowing for the calculations of electronic transport. Our results show that the proposed device has high sensitivity towards the presence of DNA, and, combined with the presence of a specific DNA probe in the form of a single-strand, it presents good selectivity towards specific nucleotide sequences.
Ämnesord
- NATURVETENSKAP -- Fysik -- Den kondenserade materiens fysik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Condensed Matter Physics (hsv//eng)
Nyckelord
- DNA chip
- graphene
- QM/MM
- non-equilibrium Green's functions
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas