Sökning: onr:"swepub:oai:DiVA.org:uu-394691" >
Magnetic Resonance ...
Magnetic Resonance Imaging or Endoscopic Ultrasonography for Detection and Surveillance of Pancreatic Neuroendocrine Neoplasms in Patients with Multiple Endocrine Neoplasia Type 1?
-
- Daskalakis, Kosmas (författare)
- Uppsala universitet,Endokrinkirurgi,Univ Athens, Laiko Hosp, Endocrine Oncol Unit, Dept Propauped Internal Med 1, Athens, Greece
-
- Tsoli, Marina (författare)
- Univ Athens, Laiko Hosp, Endocrine Oncol Unit, Dept Propauped Internal Med 1, Athens, Greece
-
- Alexandraki, Krystallenia I. (författare)
- Univ Athens, Laiko Hosp, Endocrine Oncol Unit, Dept Propauped Internal Med 1, Athens, Greece
-
visa fler...
-
- Angelousi, Anna (författare)
- Karolinska Institutet
-
- Chatzellis, Eleftherios (författare)
- Univ Athens, Laiko Hosp, Endocrine Oncol Unit, Dept Propauped Internal Med 1, Athens, Greece
-
- Tsolakis, Apostolos V. (författare)
- Karolinska Inst, Dept Oncol & Pathol, Stockholm, Sweden;Karolinska Univ Hosp, CCK, Stockholm, Sweden
-
- Karoumpalis, Ioannis (författare)
- G Gennimatas Gen Hosp, Dept Gastroenterol, Athens, Greece
-
- Kolomodi, Denise (författare)
- Univ Athens, Laiko Hosp, Endocrine Oncol Unit, Dept Propauped Internal Med 1, Athens, Greece
-
- Kassi, Evanthia (författare)
- Univ Athens, Laiko Hosp, Endocrine Oncol Unit, Dept Propauped Internal Med 1, Athens, Greece;Natl & Kapodistrian Nivers Athens, Med Sch, Dept Biol Chem, Athens, Greece
-
- Kaltsas, Gregory (författare)
- Univ Athens, Laiko Hosp, Endocrine Oncol Unit, Dept Propauped Internal Med 1, Athens, Greece;Univ Warwick, Univ Hosp, Warwick Med Sch, Clin Sci Res Labs, Coventry, W Midlands, England;Coventry Univ, Fac Hlth & Life Sci, Ctr Appl Biol & Exercise Sci, Coventry, W Midlands, England
-
visa färre...
-
(creator_code:org_t)
- 2019-07-11
- 2019
- Engelska.
-
Ingår i: Hormone and Metabolic Research. - : GEORG THIEME VERLAG KG. - 0018-5043 .- 1439-4286. ; 51:9, s. 580-585
- Relaterad länk:
-
http://www.thieme-co...
-
visa fler...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- Our aim was to compare the clinical utility of Magnetic Resonance Imaging (MRI) and Endoscopic Ultrasonography (EUS) in identifying Pancreatic Neurondocrine Neoplasms (PanNENs) and monitoring size alterations in Multiple Endocrine Neoplasia type 1 (MEN1) patients. Thirty-one MEN1 patients with PanNENs and concurrent screening by EUS and abdominal MRI were included and 129 pancreatic lesions were detected in total. MRI detected fewer lesions than EUS (n=73 vs. 110, p=0.006). MRI sensitivity and specificity compared to EUS at 20 and 10 mm cut-offs of maximal lesion diameter were 96 and 88% (20 mm cut-off) and 90 and 82%(10 mm cut-off), respectively (concordance rates of 97 and 87% and Cohen's kappa=0.912 and 0.718, respectively). Lesions<1 cm were more often detected with EUS (p=0.025). Data from sequential concurrent imaging on lesion growth rate [n=7 (mean +/- SD: 2 mm/year +/- 3.4 mm vs. 1.9 mm/year +/- 3.6 mm)] over a period of at least two years as well as pathology data in connection to preoperative concurrent imaging were available in a small number of patients (n=7, p=0.933 for mean differences in maximal lesion diameter). MRI of the pancreas was more readily available and less expensive than EUS in an outpatient setting. In conclusion, MRI performs well compared to EUS for the detection and subsequent surveillance of MEN1-related panNENs larger than 10 mm and seems to be cost-effective. Both modalities could be used at initial assessment and MRI alone could be utilized thereafter in patient surveillance. EUS retains its value in surgical planning and the detection of small mostly functional PanNENs.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Nyckelord
- multiple endocrine neoplasia type 1
- neuroendocrine tumor
- magnetic resonance imaging
- endoscopic ultrasonography
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Daskalakis, Kosm ...
-
Tsoli, Marina
-
Alexandraki, Kry ...
-
Angelousi, Anna
-
Chatzellis, Elef ...
-
Tsolakis, Aposto ...
-
visa fler...
-
Karoumpalis, Ioa ...
-
Kolomodi, Denise
-
Kassi, Evanthia
-
Kaltsas, Gregory
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Gastroenterologi
- Artiklar i publikationen
-
Hormone and Meta ...
- Av lärosätet
-
Uppsala universitet
-
Karolinska Institutet